SCHEMBL21793205

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21793191	0.89	PDK2 (0.48)	PDK2PDE4DESR1ESR2MEN1
	SCHEMBL14823249	0.89	PDK2 (0.42)	LTA4HNR1H2BAXPDK2MEN1
	SCHEMBL3813379	0.89	PDK2 (0.50)	PDK2PDE4DESR1ESR2MEN1
	SCHEMBL6441263	0.89	PDK2 (0.42)	LTA4HNR1H2BAXPDK2MEN1
	SCHEMBL29523761	0.89	PDK2 (0.50)	PDK2PDE4DESR1ESR2MEN1
	SCHEMBL20960622	0.88	LTA4H (0.60)	LTA4HNR1H2BAXPDK2PDE4D
	SCHEMBL17010782	0.85	LTA4H (0.42)	LTA4HNR1H2BAXPDK2PDE4D
	SCHEMBL13129740	0.85	PDK2 (0.43)	LTA4HPDK2MEN1KMT2AMAPT
	SCHEMBL22197216	0.85	PDK2 (0.44)	PDK2PDE4DESR1ESR2MEN1
	SCHEMBL16902923	0.85	LTA4H (0.53)	LTA4HNR1H2BAXPDK2PDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.