Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 5/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | BAX | Q07812 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14823249 | 1.00 | PDK2 (0.42) | PDK2MAOAMAOBLTA4HTSHR | |
| SCHEMBL13129740 | 0.95 | PDK2 (0.43) | PDK2MAOAMAOBLTA4HTSHR | |
| SCHEMBL13129739 | 0.92 | PDK2 (0.37) | PDK2MAOAMAOBLTA4HTSHR | |
| SCHEMBL21793205 | 0.89 | LTA4H (0.46) | PDK2MAOAMAOBLTA4HTSHR | |
| SCHEMBL22197320 | 0.86 | LTA4H (0.50) | PDK2MAOAMAOBLTA4HTSHR | |
| SCHEMBL22197292 | 0.86 | ALDH1A1 (0.40) | PDK2MAOAMAOBMCL1PGR | |
| SCHEMBL21793629 | 0.86 | PDK2 (0.41) | PDK2MAOAMAOBPGRMAPT | |
| SCHEMBL1307887 | 0.84 | PDK2 (0.47) | PDK2MAPTKDM4EMEN1LMNA | |
| SCHEMBL29540116 | 0.84 | PDK2 (0.47) | PDK2MAPTKDM4EMEN1LMNA | |
| SCHEMBL23713945 | 0.83 | PDK2 (0.39) | PDK2MAOAMAOBPGRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410243-B2 | Aromatic ether-containing fluorene monomers, processes for their preparation and polymerization thereof | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2013-04-02 | — | — | US | disclosed |
| US-20100240856-A1 | Aromatic Ether-Containing Fluorene Monomers, Processes for their Preparation and Polymerization Thereof | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2010-09-23 | — | — | US | disclosed |
| US-6900285-B2 | Fluorene-containing polymers and compounds useful in the preparation thereof | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-05-31 | — | — | US | disclosed |
| US-20030208032-A1 | Fluorene-containing polymers and compounds useful in the preparation thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-11-06 | — | — | US | disclosed |
| US-6514632-B1 | Electroluminescent films and coatings for light emitting diodes; efficiency | DOW GLOBAL TECHNOLOGIES INC. | 2003-02-04 | — | — | US | disclosed |
| US-6512083-B1 | Film prepared from the polymers of this invention. this invention is a light-emitting diode comprised of one or more layers of polymer films, at least one of which is derived from the oligomers and polymers of the invention. | DOW GLOBAL TECHNOLOGIES INC. | 2003-01-28 | — | — | US | disclosed |
| US-6362310-B1 | LIGHT EMITTING POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-03-26 | — | — | US | disclosed |
| US-6255449-B1 | PROCESS FOR PREPARING POLYMERS HAVING AT LEAST THREE FLUORENE GROUPS IN BACKBONE, WHICH COMPRISES HEATING 2,7-DIHALO-9-SUBSTITUTED FLUORENES UNDER REACTION CONDITIONS SUFFICIENT TO FORM SAID POLYMERS | THE DOW CHEMICAL COMPANY | 2001-07-03 | — | — | US | disclosed |
| US-6169163-B1 | NOVEL 2,7-DIHALOFLUORENES SUBSTITUTED AT 9-POSITION | THE DOW CHEMICAL COMPANY | 2001-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240856-A1 | Aromatic Ether-Containing Fluorene Monomers, Processes for their Preparation and Polymerization Thereof | TYR, PAH, AFF4 | PDK2 2716/4885MAOA 638/4885MAOB 501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.