Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.58 |
| ▸ | CETP | P11597 | 3/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 4/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL205602 | 0.88 | CETP (0.61) | DHODHCETPESR2RAB9AMAPT | |
| SCHEMBL9126988 | 0.88 | DHODH (0.70) | DHODHCETPESR2RAB9AMAPT | |
| SCHEMBL24871288 | 0.88 | CETP (0.58) | DHODHCETPESR2RAB9AMAPT | |
| SCHEMBL2957776 | 0.87 | DHODH (0.58) | DHODHCETPESR2RAB9AMAPT | |
| SCHEMBL2957208 | 0.87 | CETP (0.60) | DHODHCETPESR2RAB9AMAPT | |
| SCHEMBL2959887 | 0.87 | HTR3A (0.58) | DHODHCETPESR2RAB9AMAPT | |
| SCHEMBL204097 | 0.86 | DHODH (0.60) | DHODHCETPESR2RAB9AMAPT | |
| SCHEMBL204884 | 0.86 | CETP (0.56) | DHODHCETPESR2RAB9AMAPT | |
| SCHEMBL21776841 | 0.85 | DHODH (0.58) | DHODHCETPESR2RAB9AMAPT | |
| SCHEMBL3920472 | 0.84 | CETP (0.55) | DHODHCETPESR2RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210395242-A1 | HETEROCYCLIC COMPOUNDS AS AHR MODULATORS | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2021-12-23 | — | — | US | disclosed |
| WO-2020043880-A1 | HETEROCYCLIC COMPOUNDS AS AHR MODULATORS | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2020-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210395242-A1 | HETEROCYCLIC COMPOUNDS AS AHR MODULATORS | AHR, ARNT, AIPL1 | DHODH 609/4885CETP 4019/4885ESR2 920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.