Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAP1LC3B | Q9GZQ8 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | LDHB | P07195 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21774003 | 0.83 | MAP1LC3B (0.70) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL21795165 | 0.81 | MAP1LC3B (0.68) | KMT2AMEN1SMN1; SMN2MAP1LC3BHPGD | |
| SCHEMBL21795161 | 0.79 | MAP1LC3B (0.67) | ALDH1A1KMT2AMEN1MAP1LC3BMAPT | |
| SCHEMBL428339 | 0.78 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL1177339 | 0.75 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL2474471 | 0.74 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL14492202 | 0.74 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL10815794 | 0.73 | CYP19A1 (0.66) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL1176975 | 0.72 | MAPT (0.56) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL21822038 | 0.71 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200069609-A1 | METHOD FOR COVALENT BOND MODIFYING MAMMALIAN ATG8 HOMOLOGUE | Wigen Biomedicine Technology (shanghai) Co., Ltd. (CN) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200069609-A1 | METHOD FOR COVALENT BOND MODIFYING MAMMALIAN ATG8 HOMOLOGUE | ATG7, ATG4A, MLST8 | ALDH1A1 4094/4885KMT2A 1235/4885MEN1 3270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.