Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.47 |
| ▸ | PPM1B | O75688 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21795656 | 1.00 | SLC6A3 (0.47) | SLC6A3SLC6A4PPM1BPTPN1PPP1CC | |
| SCHEMBL15420706 | 0.85 | SLC6A3 (0.48) | SLC6A3SLC6A4ALDH1A1 | |
| SCHEMBL24233328 | 0.76 | ALDH1A1 (0.50) | ALDH1A1KDM4ENPC1HPGDTSHR | |
| SCHEMBL23986820 | 0.76 | ALDH1A1 (0.50) | ALDH1A1KDM4ENPC1HPGDTSHR | |
| SCHEMBL29374639 | 0.76 | ALDH1A1 (0.50) | ALDH1A1KDM4ENPC1HPGDTSHR | |
| SCHEMBL29374264 | 0.76 | ALDH1A1 (0.50) | ALDH1A1KDM4ENPC1HPGDTSHR | |
| SCHEMBL21104774 | 0.74 | ALDH1A1 (0.47) | SLC6A3SLC6A4ALDH1A1KDM4ENPC1 | |
| SCHEMBL14341281 | 0.74 | ALDH1A1 (0.47) | SLC6A3SLC6A4ALDH1A1KDM4ENPC1 | |
| SCHEMBL14341272 | 0.74 | ALDH1A1 (0.47) | SLC6A3SLC6A4ALDH1A1KDM4ENPC1 | |
| SCHEMBL12565042 | 0.74 | ALDH1A1 (0.47) | SLC6A3SLC6A4ALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2694472-B1 | SULFONAMIDE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2020-03-11 | — | — | EP | disclosed |