Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23986820 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KDM4ESMN1; SMN2HPGDTSHR | |
| SCHEMBL29374639 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KDM4ESMN1; SMN2HPGDTSHR | |
| SCHEMBL24233328 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KDM4ESMN1; SMN2HPGDTSHR | |
| SCHEMBL24233327 | 0.82 | KDM4E (0.46) | KDM4E | |
| SCHEMBL23611010 | 0.82 | KDM4E (0.46) | KDM4E | |
| SCHEMBL13920529 | 0.76 | ALDH1A1 (0.54) | ALDH1A1KDM4ESMN1; SMN2HPGDTSHR | |
| SCHEMBL13920527 | 0.76 | ALDH1A1 (0.54) | ALDH1A1KDM4ESMN1; SMN2HPGDTSHR | |
| SCHEMBL21795656 | 0.76 | SLC6A3 (0.47) | ALDH1A1KDM4ESMN1; SMN2HPGDTSHR | |
| SCHEMBL21795655 | 0.76 | SLC6A3 (0.47) | ALDH1A1KDM4ESMN1; SMN2HPGDTSHR | |
| SCHEMBL21104774 | 0.75 | ALDH1A1 (0.47) | ALDH1A1KDM4ESMN1; SMN2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904333-B1 | METHOD FOR PREPARING (2S,3S)-3-AMINO-BICYCLO[2.2.2]OCTANE-2-CARBOXYLATE | GUANGDONG RAFFLES PHARMATECH CO LTD (CN) | 2024-12-04 | — | — | EP | disclosed |
| US-20220033344-A1 | METHOD FOR PREPARING (2S,3S)-3-AMINO-BICYCLO[2.2.2]OCTANE-2-CARBOXYLATE | GUANGDONG RAFFLES PHARMATECH CO., LTD (CN) | 2022-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220033344-A1 | METHOD FOR PREPARING (2S,3S)-3-AMINO-BICYCLO[2.2.2]OCTANE-2-CARBOXYLATE | ACMSD, HCAR2, SLC3A2 | ALDH1A1 1227/4885KDM4E 1503/4885SMN1; SMN2 3340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.