Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15420021 | 1.00 | RAB9A (0.37) | RAB9ANPC1GRIA2ALDH1A1HPGD | |
| SCHEMBL15420610 | 0.90 | GRIA2 (0.38) | RAB9ANPC1GRIA2ALDH1A1HPGD | |
| SCHEMBL15420213 | 0.89 | LMNA (0.38) | RAB9ANPC1GRIA2ALDH1A1HPGD | |
| SCHEMBL15420302 | 0.89 | SCN9A (0.40) | RAB9ANPC1GRIA2ALDH1A1HPGD | |
| SCHEMBL15420860 | 0.88 | KDM4E (0.41) | ALDH1A1HPGDTNFLMNAMAPK1 | |
| SCHEMBL15420030 | 0.81 | SCN9A (0.35) | RAB9ANPC1ALDH1A1HSD17B10LMNA | |
| SCHEMBL15420636 | 0.80 | CXCR1 (0.36) | RAB9ANPC1ALDH1A1HPGDTNF | |
| SCHEMBL15420297 | 0.80 | TP53 (0.43) | NPC1LMNAMAPK1TDP1MAPT | |
| SCHEMBL15420156 | 0.80 | LMNA (0.49) | RAB9ANPC1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL15420358 | 0.80 | NPC1 (0.34) | RAB9ANPC1ALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2694472-B1 | SULFONAMIDE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2020-03-11 | — | — | EP | disclosed |