Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1035966 | 0.77 | RXRA (0.30) | RXRAGRIN1GRIN2B | |
| SCHEMBL1032886 | 0.77 | F2RL3 (0.31) | — | |
| SCHEMBL1031414 | 0.74 | GRIN1 (0.30) | GRIN1GRIN2B | |
| SCHEMBL2180070 | 0.74 | MEN1 (0.31) | — | |
| SCHEMBL1035285 | 0.74 | KDM4E (0.32) | RXRAGRIN1GRIN2B | |
| SCHEMBL2175980 | 0.74 | — | — | |
| SCHEMBL1034447 | 0.73 | HRH4 (0.30) | RXRAGRIN1GRIN2B | |
| SCHEMBL2178393 | 0.72 | — | — | |
| SCHEMBL2179939 | 0.71 | MEN1 (0.34) | — | |
| SCHEMBL2178912 | 0.70 | SCN5A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166162-A1 | 1,2-Benzisothiazole Compounds Useful for Combating Animal Pests | BASF SE (DE) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166162-A1 | 1,2-Benzisothiazole Compounds Useful for Combating Animal Pests | GLRX3, CBR3, PRDX1 | RXRA 405/4885GRIN1 407/4885GRIN2B 1311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.