Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2180070 | 0.87 | MEN1 (0.31) | — | |
| SCHEMBL2180024 | 0.86 | RXRA (0.34) | KDM4EMAPTRXRAGRIN1GRIN2B | |
| SCHEMBL1035966 | 0.81 | RXRA (0.30) | RXRAGRIN1GRIN2B | |
| SCHEMBL2177830 | 0.81 | ALDH1A1 (0.38) | — | |
| SCHEMBL1032886 | 0.78 | F2RL3 (0.31) | KDM4EMAPTPIK3CA | |
| SCHEMBL1031414 | 0.76 | GRIN1 (0.30) | GRIN1GRIN2B | |
| SCHEMBL2175980 | 0.75 | — | — | |
| SCHEMBL2179010 | 0.75 | MEN1 (0.34) | RXRAGRIN1GRIN2B | |
| SCHEMBL1034447 | 0.74 | HRH4 (0.30) | MAPTRXRAGRIN1GRIN2B | |
| SCHEMBL2178393 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299262-B2 | Pyridylmethyl-sulfonamide compounds | BASF SE (DE) | 2012-10-30 | — | — | US | claimed |
| JP-2011506281-A | — | — | 2011-03-03 | — | — | JP | claimed |
| EP-2262794-A1 | SULFONAMIDE COMPOUNDS AND THEIR USE AS FUNGICIDE | BASF SE (DE) | 2010-12-22 | — | — | EP | claimed |
| US-20100317516-A1 | Sulfonamide Compounds And Their Use As Fungicide | BASF SE (DE) | 2010-12-16 | — | — | US | claimed |
| US-20100249077-A1 | Pyridylmethyl-Sulfonamide Compounds | BASF SE (DE) | 2010-09-30 | — | — | US | claimed |
| EP-2231605-A1 | PYRIDYLMETHYL-SULFONAMIDE COMPOUNDS | BASF SE (DE) | 2010-09-29 | — | — | EP | claimed |
| WO-2009103650-A1 | SULFONAMIDE COMPOUNDS AND THEIR USE AS FUNGICIDE | BASF SE (DE) | 2009-08-27 | — | — | WO | claimed |
| WO-2009071448-A1 | PYRIDYLMETHYL-SULFONAMIDE COMPOUNDS | BASF SE (DE) | 2009-06-11 | — | — | WO | claimed |
| WO-2009071449-A1 | PYRIDYLMETHYL-SULFONAMIDE COMPOUNDS | BASF SE (DE) | 2009-06-11 | — | — | WO | claimed |
| US-8299262-B2 | Pyridylmethyl-sulfonamide compounds | BASF SE (DE) | 2012-10-30 | — | — | US | disclosed |
| US-20110166162-A1 | 1,2-Benzisothiazole Compounds Useful for Combating Animal Pests | BASF SE (DE) | 2011-07-07 | — | — | US | disclosed |
| EP-2297134-A1 | SUBSTITUTED PYRIDIN-4 -YL-METHYL SULFONAMIDES AS FUNGICIDES | BASF SE (DE) | 2011-03-23 | — | — | EP | disclosed |
| US-20110065577-A1 | Substituted pyridin-4-yl-methyl sulfonamides as fungicides | BASF SE (DE) | 2011-03-17 | — | — | US | disclosed |
| US-20110045974-A1 | Substituted Triazinylmethyl Sulfonamides | BASF SE (DE) | 2011-02-24 | — | — | US | disclosed |
| WO-2009141292-A1 | SUBSTITUTED HETEROARYLMETHYL SULFONAMIDES | BASF SE (DE) | 2009-11-26 | — | — | WO | disclosed |
| WO-2009124903-A1 | SUBSTITUTED PYRIDAZINYLMETHYL SULFONAMIDES | BASF SE (DE) | 2009-10-15 | — | — | WO | disclosed |
| WO-2009112533-A1 | SUBSTITUTED TRIAZINYLMETHYL SULFONAMIDES | BASF SE (DE) | 2009-09-17 | — | — | WO | disclosed |
| WO-2009103650-A1 | SULFONAMIDE COMPOUNDS AND THEIR USE AS FUNGICIDE | BASF SE (DE) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009071448-A1 | PYRIDYLMETHYL-SULFONAMIDE COMPOUNDS | BASF SE (DE) | 2009-06-11 | — | — | WO | disclosed |
| WO-2009071449-A1 | PYRIDYLMETHYL-SULFONAMIDE COMPOUNDS | BASF SE (DE) | 2009-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317516-A1 | Sulfonamide Compounds And Their Use As Fungicide | STS, ARSA, CYP4X1 | KDM4E 705/4885MAPT 4057/4885PIK3CA 914/4885 |
| US-20110166162-A1 | 1,2-Benzisothiazole Compounds Useful for Combating Animal Pests | GLRX3, CBR3, PRDX1 | KDM4E 4261/4885MAPT 4632/4885PIK3CA 4435/4885 |
| US-20110045974-A1 | Substituted Triazinylmethyl Sulfonamides | STS, TST, TPST2 | KDM4E 1795/4885MAPT 2320/4885PIK3CA 1858/4885 |
| US-20100249077-A1 | Pyridylmethyl-Sulfonamide Compounds | CBR3, CBR1, CBS | KDM4E 2704/4885MAPT 4200/4885PIK3CA 1277/4885 |
| US-20110065577-A1 | Substituted pyridin-4-yl-methyl sulfonamides as fungicides | CYP4X1, PNPO, PADI1 | KDM4E 302/4885MAPT 3891/4885PIK3CA 986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.