SCHEMBL21798548

SCHEMBL21798548

CC(C)/C(c1ccccc1)=[Hf](\C1=CC=CC1)C1c2cc(C(C)(C)C)ccc2-c2ccc(C(C)(C)C)cc21.c1ccc(CCc2ccccc2)cc1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ESRRG P62508 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21798551 0.94 NPC1 (0.33) NPC1RAB9A
Hydrochloric Acid SCHEMBL21797759 0.93 NPC1 (0.31) NPC1RAB9A
SCHEMBL21295207 0.84 NPC1 (0.30) ESRRGNPC1RAB9A
SCHEMBL21295245 0.83
SCHEMBL21295224 0.83 NPC1 (0.31) ESRRGNPC1RAB9A
SCHEMBL6231439 0.83 NPC1 (0.32) NPC1RAB9A
SCHEMBL21295251 0.83
Hydrochloric Acid SCHEMBL23209652 0.82 NPC1 (0.30) ESRRGNPC1RAB9A
Hydrochloric Acid SCHEMBL21797754 0.82 NPC1 (0.31) NPC1RAB9A
SCHEMBL21295213 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11639399-B2 Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process BOREALIS AG (AT) 2023-05-02 US claimed
US-11530280-B2 Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process BOREALIS AG (AT) 2022-12-20 US claimed
US-20200079884-A1 NEW CATALYST SYSTEM FOR PRODUCING POLYETHYLENE COPOLYMERS IN A HIGH TEMPERATURE SOLUTION POLYMERIZATION PROCESS BOREALIS AG (AT) 2020-03-12 US claimed
US-11639399-B2 Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process BOREALIS AG (AT) 2023-05-02 US disclosed
US-11530280-B2 Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process BOREALIS AG (AT) 2022-12-20 US disclosed
US-20200079884-A1 NEW CATALYST SYSTEM FOR PRODUCING POLYETHYLENE COPOLYMERS IN A HIGH TEMPERATURE SOLUTION POLYMERIZATION PROCESS BOREALIS AG (AT) 2020-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11639399-B2 Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process C1S, SIGMAR1, C1R ESRRG 462/4885NPC1 3202/4885RAB9A 3725/4885
US-11530280-B2 Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process C1S, AP3S1, C5 ESRRG 465/4885NPC1 3247/4885RAB9A 3705/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.