Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6231439 | 0.99 | NPC1 (0.32) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL18420603 | 0.92 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL21270131 | 0.91 | NPC1 (0.34) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL8768573 | 0.90 | NPC1 (0.31) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL18420756 | 0.88 | TRPV1 (0.33) | KIF11 | |
| Hydrochloric Acid SCHEMBL21797759 | 0.88 | NPC1 (0.31) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL18420855 | 0.87 | CES2 (0.37) | ALDH1A1L3MBTL1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL21295239 | 0.86 | KIF11 (0.31) | KIF11 | |
| Hydrochloric Acid SCHEMBL21295209 | 0.86 | KIF11 (0.31) | KIF11 | |
| SCHEMBL20972328 | 0.85 | NR1H2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630658-B2 | Low crystallinity ethylene-vinylcyclohexane copolymers | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2026-05-19 | — | — | US | disclosed |
| US-12209176-B2 | Ethylene-cyclic mono olefin copolymerizations | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2025-01-28 | — | — | US | disclosed |
| US-20240052147-A1 | ETHYLENE-CYCLIC MONO OLEFIN COPOLYMERIZATIONS | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2024-02-15 | — | — | US | disclosed |
| US-20240002561-A1 | LOW CRYSTALLINITY ETHYLENE-VINYLCYCLOHEXANE COPOLYMERS | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2024-01-04 | — | — | US | disclosed |
| US-20230416429-A1 | HIGH CRYSTALLINITY ETHYLENE-VINYLCYCLOHEXANE COPOLYMERS | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2023-12-28 | — | — | US | disclosed |
| US-11827775-B2 | Ethylene-cyclic mono olefin copolymerizations | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2023-11-28 | — | — | US | disclosed |
| EP-3601384-B1 | ALUMINOXANE-ACTIVATED METALLOCENE CATALYSTS | BOREALIS AG (AT) | 2023-05-03 | — | — | EP | disclosed |
| EP-3555148-B1 | CATALYST SYSTEM FOR PRODUCING POLYETHYLENE COPOLYMERS IN A HIGH TEMPERATURE SOLUTION POLYMERIZATION PROCESS | BOREALIS AG (AT) | 2023-04-05 | — | — | EP | disclosed |
| US-11560440-B2 | Aluminoxane-activated metallocene catalysts | BOREALIS AG (AT) | 2023-01-24 | — | — | US | disclosed |
| WO-2022123414-A1 | LOW CRYSTALLINITY ETHYLENE-VINYLCYCLOHEXANE COPOLYMERS | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2022-06-16 | — | — | WO | disclosed |
| WO-2022123413-A1 | HIGH CRYSTALLINITY ETHYLENE-VINYLCYCLOHEXANE COPOLYMERS | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2022-06-16 | — | — | WO | disclosed |
| US-20220185923-A1 | CATALYST SYSTEM | BOREALIS AG (AT) | 2022-06-16 | — | — | US | disclosed |
| US-20220119628-A1 | ETHYLENE-CYCLIC MONO OLEFIN COPOLYMERIZATIONS | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2022-04-21 | — | — | US | disclosed |
| US-11279781-B2 | Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process | BOREALIS AG (AT) | 2022-03-22 | — | — | US | disclosed |
| EP-3953403-A1 | CATALYST SYSTEM | Borealis AG (AT) | 2022-02-16 | — | — | EP | disclosed |
| US-20210095057-A1 | ALUMINOXANE-ACTIVATED METALLOCENE CATALYSTS | BOREALIS AG (AT) | 2021-04-01 | — | — | US | disclosed |
| WO-2020208128-A1 | CATALYST SYSTEM | BOREALIS AG (AT) | 2020-10-15 | — | — | WO | disclosed |
| WO-2020079552-A1 | ETHYLENE-CYCLIC MONO OLEFIN COPOLYMERIZATIONS | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2020-04-23 | — | — | WO | disclosed |
| US-20200079887-A1 | CATALYST SYSTEM FOR PRODUCING POLYETHYLENE COPOLYMERS IN A HIGH TEMPERATURE SOLUTION POLYMERIZATION PROCESS | BOREALIS AG (AT) | 2020-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11279781-B2 | Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process | OPRM1, SIGMAR1, AP2S1 | NPC1 2435/4885ALDH1A1 4096/4885PLA2G1B 4065/4885 |
| US-20220185923-A1 | CATALYST SYSTEM | CPNE4, INF2, CAD | NPC1 2085/4885ALDH1A1 2581/4885PLA2G1B 2154/4885 |
| US-12630658-B2 | Low crystallinity ethylene-vinylcyclohexane copolymers | HVCN1, H1-0, SUV39H1 | NPC1 3029/4885ALDH1A1 922/4885PLA2G1B 1502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.