Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CFTR | P13569 | 3/20 | 0.50 |
| ▸ | IKBKB | O14920 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29481401 | 0.86 | KDM4E (0.55) | ALDH1A1KDM4EHSD17B10GAAMAPT | |
| SCHEMBL1015993 | 0.86 | KDM4E (0.55) | ALDH1A1KDM4EHSD17B10GAAMAPT | |
| SCHEMBL7529190 | 0.86 | KDM4E (0.66) | ALDH1A1KDM4EHSD17B10GAAMAPT | |
| SCHEMBL29188757 | 0.85 | SLC6A4 (0.49) | ALDH1A1KDM4EHSD17B10GAAMAPT | |
| SCHEMBL29543806 | 0.85 | KDM4E (0.54) | ALDH1A1KDM4EHSD17B10GAAMAPT | |
| SCHEMBL421466 | 0.84 | IKBKB (0.65) | ALDH1A1KDM4EHSD17B10GAAMAPT | |
| SCHEMBL13525215 | 0.84 | ALDH1A1 (0.53) | ALDH1A1KDM4EHSD17B10GAAMAPT | |
| SCHEMBL3876452 | 0.83 | TAAR1 (0.51) | KDM4EIKBKBTAAR1KMT2AGFER | |
| SCHEMBL165608 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KDM4EHSD17B10GAAMAPT | |
| SCHEMBL21798893 | 0.82 | KDM4E (0.54) | ALDH1A1KDM4EHSD17B10GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632913-A1 | CARBOXYLIC ACID DERIVATIVES OF PYRIDOQUINAZOLINES USEFUL AS PROTEIN KINASE INHIBITORS | Oncostellae, S.L. (ES) | 2020-04-08 | — | — | EP | disclosed |
| US-20200079773-A1 | CARBOXYLIC ACID DERIVATIVES OF PYRIDOQUINAZOLINES USEFUL AS PROTEIN KINASE INHIBITORS | ONCOSTELLAE, S.L. (ES) | 2020-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200079773-A1 | CARBOXYLIC ACID DERIVATIVES OF PYRIDOQUINAZOLINES USEFUL AS PROTEIN KINASE INHIBITORS | MAP4K2, MAP3K1, MAP4K1 | ALDH1A1 2104/4885KDM4E 1110/4885HSD17B10 3480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.