Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | GAA | P10253 | 5/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.61 |
| ▸ | CFTR | P13569 | 3/20 | 0.56 |
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | IKBKB | O14920 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | FADS1 | O60427 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1015993 | 0.86 | KDM4E (0.55) | ALDH1A1KDM4EGAAHSD17B10MAPT | |
| SCHEMBL29481401 | 0.86 | KDM4E (0.55) | ALDH1A1KDM4EGAAHSD17B10MAPT | |
| SCHEMBL1035480 | 0.85 | ALDH1A1 (0.66) | ALDH1A1KDM4EGAAHSD17B10MAPT | |
| SCHEMBL29543806 | 0.85 | KDM4E (0.54) | ALDH1A1KDM4EGAAHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL7729822 | 0.84 | ALDH1A1 (0.64) | ALDH1A1KDM4EGAAHSD17B10MAPT | |
| SCHEMBL12846981 | 0.82 | ALDH1A1 (0.82) | ALDH1A1KDM4EGAAHSD17B10MAPT | |
| SCHEMBL21798946 | 0.82 | ALDH1A1 (0.51) | ALDH1A1KDM4EGAAHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL2454106 | 0.82 | BRAF (0.57) | ALDH1A1KDM4EGAAHSD17B10MAPT | |
| SCHEMBL2708451 | 0.82 | SLC6A4 (0.51) | ALDH1A1KDM4EGAAHSD17B10MAPT | |
| SCHEMBL30301996 | 0.82 | SLC6A4 (0.51) | ALDH1A1KDM4EGAAHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115490643-A | Method for synthesizing 3-dichlorophenyl-6-fluoro-2, 4 (1H, 3H) -quinazolinedione by one-pot method | 南京合创药业有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-112939802-A | Ferulic acid amide derivative, and synthesis method and application thereof | 张利辉 | 2021-06-11 | — | — | CN | claimed |
| CN-106349092-B | Synthesis method of 2-amino-5-fluorobenzoic acid methyl ester | 泰州祥泰康华医药科技有限公司 | 2018-07-03 | — | — | CN | claimed |
| CN-106349092-A | Synthesis method of 2-amino-5-fluorobenzoicacid methyl ester | 叶芳 | 2017-01-25 | — | — | CN | claimed |
| JP-8325240-A | — | — | None | — | — | JP | disclosed |
| WO-2026104681-A1 | NEW SULFONAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2026-05-21 | — | — | WO | disclosed |
| EP-4743465-A1 | BICYCLIC MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. Hoffmann-La Roche AG (CH) | 2026-05-20 | — | — | EP | disclosed |
| CN-121779224-A | Preparation method of 5-fluoro-2-iodobenzoic acid | 安庆双启医药科技有限公司 | 2026-04-03 | — | — | CN | disclosed |
| CN-120117999-A | Fluorotranilast derivatives and medical application thereof | 中国药科大学 | 2025-06-10 | — | — | CN | disclosed |
| US-20250136568-A1 | FUSED HETEROCYCLIC COMPOUNDS AS PI3KALPHA INHIBITORS | NANJING ZENSHINE PHARMACEUTICALS CO., LTD. (CN) | 2025-05-01 | — | — | US | disclosed |
| WO-2025040167-A1 | PHOSPHOINOSITIDE 3-KINASE ALLOSTERIC INHIBITOR FOR TREATING DISEASE RELATED TO PI3K REGULATION | 上海艾力斯医药科技股份有限公司 | 2025-02-27 | — | — | WO | disclosed |
| WO-2025023769-A1 | NOVEL SYNTHESIS METHOD OF 18F-RUCAPARIB | 고려대학교 산학협력단 | 2025-01-30 | — | — | WO | disclosed |
| EP-0647615-B1 | Process for the preparation of 5-fluoroanthranilic acid alkyl esters and or 5-fluoroanthranilic acid | HOECHST AG (DE) | 1997-05-28 | — | — | EP | disclosed |
| JP-H08325240-A | SUBSTITUTED 3-ARYLQUINAZOLINE-2,4-DIONE | HOECHST AG | 1996-12-10 | — | — | JP | disclosed |
| EP-0742213-A1 | Process for the preparation of substituted 3-arylquinazolin-2,4-diones | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-11-13 | — | — | EP | disclosed |
| US-5543550-A | NITRATING ALKYL ESTER OF 3-FLUOROBENZOIC ACID DISSOLVED IN SOLVENT-FREE SULFURIC ACID, THEN ADDING WATER, SEPARATION, HYDROLYSIS, PRESSURIZED CATALYTIC HYDROGENATION OF THE NITRATED ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-08-06 | — | — | US | disclosed |
| EP-0647615-A1 | Process for the preparation of 5-fluoroanthranilic acid alkyl esters and or 5-fluoroanthranilic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-04-12 | — | — | EP | disclosed |
| EP-0638075-A1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |
| WO-1994019335-A1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-01 | — | — | WO | disclosed |
| US-4233305-A | ANALGESICS | ROUSSEL UCLAF (FR) | 1980-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250136568-A1 | FUSED HETEROCYCLIC COMPOUNDS AS PI3KALPHA INHIBITORS | PIK3CA, PIK3CD, PIK3CB | ALDH1A1 1605/4885KDM4E 1884/4885GAA 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.