Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | FPR1 | P21462 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22292210 | 0.80 | KDM4E (0.62) | KDM4ETDP1L3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL28565686 | 0.75 | ALDH1A1 (0.50) | KDM4ETDP1L3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL28883896 | 0.73 | KDM4E (0.54) | KDM4ETDP1L3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL10102706 | 0.73 | KDM4E (0.52) | KDM4ETDP1L3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL28913232 | 0.73 | ALDH1A1 (0.51) | KDM4ETDP1L3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL17111452 | 0.72 | SMN1; SMN2 (0.51) | KDM4ETDP1L3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL17111582 | 0.72 | KDM4E (0.51) | KDM4ETDP1L3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL28313467 | 0.72 | ALDH1A1 (0.52) | KDM4ETDP1L3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL28958166 | 0.71 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL1993219 | 0.71 | KDM4E (0.49) | KDM4ETDP1L3MBTL1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10730838-B2 | Green preparation method for quinoline compounds | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2020-08-04 | — | — | US | disclosed |
| US-20200079737-A1 | GREEN PREPARATION METHOD FOR QUINOLINE COMPOUNDS | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2020-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200079737-A1 | GREEN PREPARATION METHOD FOR QUINOLINE COMPOUNDS | NQO1, TYR, ABCG2 | KDM4E 3307/4885TDP1 4628/4885L3MBTL1 4877/4885 |
| US-10730838-B2 | Green preparation method for quinoline compounds | NQO1, TYR, ABCG2 | KDM4E 3307/4885TDP1 4628/4885L3MBTL1 4877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.