Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL715856 | 0.78 | MAPT (0.42) | MAPTKDM4EMAPK1XBP1CHEK1 | |
| SCHEMBL21799208 | 0.71 | MAPT (0.59) | MAPTKDM4EMAPK1XBP1CHEK1 | |
| SCHEMBL11310071 | 0.70 | MAPT (0.52) | MAPTKDM4EMAPK1XBP1ALDH1A1 | |
| SCHEMBL16190872 | 0.67 | MAPT (0.59) | MAPTKDM4EMAPK1XBP1ALDH1A1 | |
| SCHEMBL715857 | 0.67 | MAPT (0.44) | MAPTKDM4EMAPK1XBP1ALDH1A1 | |
| SCHEMBL12224228 | 0.67 | MAPT (0.59) | MAPTKDM4EMAPK1XBP1ALDH1A1 | |
| SCHEMBL16178655 | 0.67 | MAPT (0.70) | MAPTKDM4EMAPK1XBP1CHEK1 | |
| SCHEMBL12176236 | 0.64 | ALDH1A1 (0.46) | MAPTKDM4EMAPK1XBP1ALDH1A1 | |
| SCHEMBL16193326 | 0.62 | ALDH1A1 (0.44) | MAPTKDM4EMAPK1XBP1CHEK1 | |
| SCHEMBL973230 | 0.62 | KMT2A (0.50) | MAPTKDM4EMAPK1XBP1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200079802-A1 | ORGANOSILICON ON SOLID OXIDES, AND RELATED COMPLEXES, COMPOSITIONS, METHODS AND SYSTEMS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-03-12 | — | — | US | claimed |
| US-20200079802-A1 | ORGANOSILICON ON SOLID OXIDES, AND RELATED COMPLEXES, COMPOSITIONS, METHODS AND SYSTEMS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200079802-A1 | ORGANOSILICON ON SOLID OXIDES, AND RELATED COMPLEXES, COMPOSITIONS, METHODS AND SYSTEMS | HAO2, AOC3, OSTC | MAPT 4087/4885KDM4E 4579/4885MAPK1 3023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.