Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2292025 | 0.83 | KMT2A (0.46) | KMT2AL3MBTL1ALDH1A1KDM4EMAPT | |
| SCHEMBL6951232 | 0.72 | CYP2A6 (0.61) | ALDH1A1KDM4EMAPTCYP3A4CYP1A2 | |
| SCHEMBL16193326 | 0.71 | ALDH1A1 (0.44) | KMT2AL3MBTL1ALDH1A1KDM4EMAPT | |
| SCHEMBL822673 | 0.71 | PCSK9 (0.68) | KMT2AALDH1A1KDM4EMAPTXBP1 | |
| SCHEMBL11310071 | 0.69 | MAPT (0.52) | KMT2AL3MBTL1ALDH1A1KDM4EMAPT | |
| Biphenyl SCHEMBL2574161 | 0.66 | ALDH1A1 (0.82) | ALDH1A1MAPK1CYP3A4CYP1A2TAAR1 | |
| Biphenyl SCHEMBL2548048 | 0.65 | ALDH1A1 (1.00) | ALDH1A1MAPTMAPK1CYP3A4CYP1A2 | |
| Biphenyl SCHEMBL1358618 | 0.65 | ALDH1A1 (1.00) | ALDH1A1MAPTMAPK1CYP3A4CYP1A2 | |
| Biphenyl SCHEMBL164 | 0.65 | ALDH1A1 (1.00) | ALDH1A1MAPTMAPK1CYP3A4CYP1A2 | |
| Biphenyl SCHEMBL4002609 | 0.65 | ALDH1A1 (1.00) | ALDH1A1MAPTMAPK1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998895-B2 | Catalysts for olefin polymerization | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-08-16 | — | — | US | disclosed |
| US-7868108-B2 | Transition metal compound, ligand system, catalyst system and process for preparing polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2011-01-11 | — | — | US | disclosed |
| US-7868108-B2 | Transition metal compound, ligand system, catalyst system and process for preparing polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2011-01-11 | — | — | US | disclosed |
| US-7868108-B2 | Transition metal compound, ligand system, catalyst system and process for preparing polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2011-01-11 | — | — | US | disclosed |
| US-20100222531-A1 | CATALYSTS FOR OLEFIN POLYMERIZATION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-09-02 | — | — | US | disclosed |
| US-20100029469-A1 | CATALYSTS FOR OLEFIN POLYMERIZATION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-02-04 | — | — | US | disclosed |
| US-20090156768-A1 | Transition Metal Compound, Ligand System, Catalyst System and Process for Preparing Polyolefins | BASELL POLYOLEFINE GMB H (DE) | 2009-06-18 | — | — | US | disclosed |
| US-20090156768-A1 | Transition Metal Compound, Ligand System, Catalyst System and Process for Preparing Polyolefins | BASELL POLYOLEFINE GMB H (DE) | 2009-06-18 | — | — | US | disclosed |
| US-20090156768-A1 | Transition Metal Compound, Ligand System, Catalyst System and Process for Preparing Polyolefins | BASELL POLYOLEFINE GMB H (DE) | 2009-06-18 | — | — | US | disclosed |
| US-7439314-B2 | Catalysts for olefin polymerization | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-21 | — | — | US | disclosed |
| EP-1192189-B1 | CATALYSTS CONTAINING N-PYRROLYL SUBSTITUTED NITROGEN DONORS | EASTMAN CHEM CO (US) | 2004-09-29 | — | — | EP | disclosed |
| US-20030225228-A1 | Catalysts containing N-pyrrolyl substituted nitrogen donors | EASTMAN CHEMICAL COMPANY | 2003-12-04 | — | — | US | disclosed |
| US-20030195110-A1 | Catalysts containing N-pyrrolyl substituted nitrogen donors | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-10-16 | — | — | US | disclosed |
| US-6559091-B1 | Metal complex ligated by a monodentate, bidentate, tridentate, or tetradentate ligand, wherein at least one of the donor atoms of the ligand is a nitrogen atom substituted by a 1-pyrrolyl or substituted 1- pyrrolyl group | EASTMAN CHEMICAL COMPANY | 2003-05-06 | — | — | US | disclosed |
| US-6545108-B1 | Ti, Zr, Hf, Cr, Mo, W, V, Nb, or Ta complex of a monodentate dianionic ligand in which a nitrogen atom is substituted by a 1-pyrrolyl and the remaining donor atoms are N, P, As, O, S, or Se | EASTMAN CHEMICAL COMPANY | 2003-04-08 | — | — | US | disclosed |
| EP-1278784-A2 | CATALYSTS CONTAINING N-PYRROLYL SUBSTITUTED NITROGEN DONORS | EASTMAN CHEMICAL COMPANY (US) | 2003-01-29 | — | — | EP | disclosed |
| EP-1192189-A2 | CATALYSTS CONTAINING N-PYRROLYL SUBSTITUTED NITROGEN DONORS | EASTMAN CHEMICAL COMPANY (US) | 2002-04-03 | — | — | EP | disclosed |
| US-20020032289-A1 | Catalysts for olefin polymerization | E.I. DU PONT DE NEMOURS AND COMPANY | 2002-03-14 | — | — | US | disclosed |
| WO-2001083571-A2 | CATALYSTS CONTAINING N-PYRROLYL SUBSTITUTED NITROGEN DONORS | EASTMAN CHEMICAL COMPANY (US) | 2001-11-08 | — | — | WO | disclosed |
| WO-2000050470-A2 | CATALYSTS CONTAINING N-PYRROLYL SUBSTITUTED NITROGEN DONORS | EASTMAN CHEMICAL COMPANY (US) | 2000-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222531-A1 | CATALYSTS FOR OLEFIN POLYMERIZATION | PORCN, PUF60, CAD | KMT2A 4665/4885L3MBTL1 2478/4885ALDH1A1 3187/4885 |
| US-20090156768-A1 | Transition Metal Compound, Ligand System, Catalyst System and Process for Preparing Polyolefins | C1S, OPRM1, OSTC | KMT2A 4162/4885L3MBTL1 251/4885ALDH1A1 3225/4885 |
| US-20100029469-A1 | CATALYSTS FOR OLEFIN POLYMERIZATION | PORCN, PUF60, CAD | KMT2A 4665/4885L3MBTL1 2478/4885ALDH1A1 3187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.