Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | CRHBP | P24387 | 2/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27798639 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KMT2AL3MBTL1CRHBPCRHR2 | |
| SCHEMBL1492534 | 0.82 | NPSR1 (0.50) | ALDH1A1KMT2AL3MBTL1ATMTDP1 | |
| SCHEMBL262538 | 0.77 | AKR1C3 (0.59) | ALDH1A1KMT2AL3MBTL1MEN1GAA | |
| SCHEMBL350868 | 0.77 | AKR1C3 (0.59) | ALDH1A1KMT2AL3MBTL1MEN1GAA | |
| SCHEMBL1343164 | 0.77 | AKR1C3 (0.59) | ALDH1A1KMT2AL3MBTL1MEN1GAA | |
| SCHEMBL21247872 | 0.76 | ALDH1A1 (0.67) | ALDH1A1KMT2AL3MBTL1CRHBPCRHR2 | |
| Hydrochloric Acid SCHEMBL18045574 | 0.76 | AKR1C3 (0.58) | ALDH1A1KMT2AL3MBTL1MEN1GAA | |
| SCHEMBL27542302 | 0.76 | MAPT (0.56) | ALDH1A1KMT2AL3MBTL1MEN1GAA | |
| SCHEMBL5841770 | 0.74 | ALDH1A1 (0.65) | ALDH1A1KMT2AL3MBTL1CRHBPCRHR2 | |
| SCHEMBL9507468 | 0.74 | CRHBP (0.64) | ALDH1A1KMT2AL3MBTL1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590919-B1 | ENAMINE COMPOUND AND USE THEREOF | JAPAN SCIENCE & TECH AGENCY (JP) | 2024-04-24 | — | — | EP | disclosed |
| US-11773052-B2 | Enamine compound and use thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2023-10-03 | — | — | US | disclosed |
| US-20200087245-A1 | ENAMINE COMPOUND AND USE THEREOF | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2020-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200087245-A1 | ENAMINE COMPOUND AND USE THEREOF | ENY2, AHR, PAH | ALDH1A1 974/4885KMT2A 2579/4885L3MBTL1 2033/4885 |
| US-11773052-B2 | Enamine compound and use thereof | ENY2, AHR, PAH | ALDH1A1 974/4885KMT2A 2579/4885L3MBTL1 2033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.