Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | CD81 | P60033 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15352277 | 1.00 | APLNR (0.42) | APLNRCD81SLC1A2SLC1A1SLC6A4 | |
| SCHEMBL6382497 | 1.00 | APLNR (0.42) | APLNRCD81SLC1A2SLC1A1SLC6A4 | |
| SCHEMBL6121809 | 1.00 | APLNR (0.42) | APLNRCD81SLC1A2SLC1A1SLC6A4 | |
| SCHEMBL965467 | 0.90 | CD81 (0.46) | APLNRCD81SLC1A2SLC1A1SLC6A4 | |
| SCHEMBL6561197 | 0.90 | CD81 (0.46) | APLNRCD81SLC1A2SLC1A1SLC6A4 | |
| SCHEMBL6561035 | 0.90 | CD81 (0.46) | APLNRCD81SLC1A2SLC1A1SLC6A4 | |
| SCHEMBL1348823 | 0.90 | CD81 (0.46) | APLNRCD81SLC1A2SLC1A1SLC6A4 | |
| SCHEMBL963070 | 0.90 | CD81 (0.46) | APLNRCD81SLC1A2SLC1A1SLC6A4 | |
| SCHEMBL10046563 | 0.86 | CD81 (0.37) | APLNRCD81SLC1A2SLC1A1SLC6A4 | |
| SCHEMBL23826187 | 0.84 | CD81 (0.36) | APLNRCD81SLC1A2SLC1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177439-A1 | NOVEL TRITERPENE DERIVATIVES AS HIV INHIBITORS | HETERO LABS LIMITED (IN) | 2022-06-09 | — | — | US | disclosed |
| US-11034718-B2 | C-3 novel triterpenone with C-17 reverse amide derivatives as HIV inhibitors | HETERO LABS LIMITED (IN) | 2021-06-15 | — | — | US | disclosed |
| US-20200087342-A1 | C-3 NOVEL TRITERPENONE WITH C-17 REVERSE AMIDE DERIVATIVES AS HIV INHIBITORS | HETERO LABS LTD (IN) | 2020-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11034718-B2 | C-3 novel triterpenone with C-17 reverse amide derivatives as HIV inhibitors | IL17A, CDK17, CCR3 | APLNR 3061/4885CD81 1298/4885SLC1A2 4766/4885 |
| US-20220177439-A1 | NOVEL TRITERPENE DERIVATIVES AS HIV INHIBITORS | CYP51A1, CCR5, HSD17B7 | APLNR 4799/4885CD81 888/4885SLC1A2 4815/4885 |
| US-20200087342-A1 | C-3 NOVEL TRITERPENONE WITH C-17 REVERSE AMIDE DERIVATIVES AS HIV INHIBITORS | IL17A, CDK17, CCR3 | APLNR 3061/4885CD81 1298/4885SLC1A2 4766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.