Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 9/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | PDE8A | O60658 | 1/20 | 0.52 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30496438 | 1.00 | YTHDC1 (0.56) | YTHDC1HPGDPDE8ACCNE2CCNE1 | |
| SCHEMBL18554311 | 0.88 | HPGD (0.67) | YTHDC1HPGDPDE8ACCNE2CCNE1 | |
| SCHEMBL29365706 | 0.88 | HPGD (0.67) | YTHDC1HPGDPDE8ACCNE2CCNE1 | |
| SCHEMBL3821565 | 0.88 | YTHDC1 (0.57) | YTHDC1HPGDPDE8ACCNE2CCNE1 | |
| SCHEMBL23635091 | 0.87 | HPGD (0.59) | YTHDC1HPGDPDE8ACCNE2CCNE1 | |
| SCHEMBL5462820 | 0.85 | ADORA2A (0.54) | YTHDC1HPGDPDE8ACCNE2CCNE1 | |
| SCHEMBL30747798 | 0.82 | CCNE2 (0.77) | YTHDC1CCNE2CCNE1CDK2CTSL | |
| SCHEMBL27249486 | 0.82 | CCNE2 (0.77) | YTHDC1CCNE2CCNE1CDK2CTSL | |
| SCHEMBL17262805 | 0.81 | YTHDC1 (0.59) | YTHDC1HPGDPDE8AADORA2ACTSL | |
| SCHEMBL17364311 | 0.80 | CDK1 (0.46) | YTHDC1PDE8ACCNE1CDK2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12157739-B2 | Hypoxanthine compounds | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2024-12-03 | — | — | US | disclosed |
| CN-112673008-B | Hypoxanthine compounds | 橘生药品工业株式会社 | 2023-07-18 | — | — | CN | disclosed |
| US-20210214357-A1 | HYPOXANTHINE COMPOUNDS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2021-07-15 | — | — | US | disclosed |
| EP-3819299-A1 | HYPOXANTHINE COMPOUND | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2021-05-12 | — | — | EP | disclosed |
| EP-3819299-A1 | HYPOXANTHINE COMPOUND | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2021-05-12 | — | — | EP | disclosed |
| CN-112673008-A | Hypoxanthine compound | 橘生药品工业株式会社 | 2021-04-16 | — | — | CN | disclosed |
| WO-2020054825-A1 | HYPOXANTHINE COMPOUND | キッセイ薬品工業株式会社 | 2020-03-19 | — | — | WO | disclosed |
| WO-2020054825-A1 | HYPOXANTHINE COMPOUND | キッセイ薬品工業株式会社 | 2020-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12157739-B2 | Hypoxanthine compounds | HPRT1, APRT, IMPDH1 | YTHDC1 651/4885HPGD 49/4885PDE8A 512/4885 |
| US-20210214357-A1 | HYPOXANTHINE COMPOUNDS | HPRT1, DHPS, PAH | YTHDC1 611/4885HPGD 56/4885PDE8A 645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.