Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 3/20 | 0.49 |
| ▸ | TDP2 | O95551 | 2/20 | 0.49 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21801765 | 0.81 | NSD2 (0.52) | NSD2TDP2TRPV3IDO1CDC25A | |
| SCHEMBL29209079 | 0.69 | MAP4K4 (0.44) | TRPV3KDM4EMAPTMAP4K4PDE10A | |
| SCHEMBL25204837 | 0.64 | MAP4K4 (0.47) | TRPV3KDM4EMAPTMAP4K4PDE10A | |
| SCHEMBL21801731 | 0.64 | MAP4K4 (0.40) | TRPV3KDM4EMAPTMAP4K4PDE10A | |
| SCHEMBL21801704 | 0.63 | TDP2 (0.61) | NSD2TDP2IDO1CDC25ACDC25B | |
| SCHEMBL1644219 | 0.63 | HRH3 (0.52) | TRPV3KDM4EMAPTMAP4K4PDE10A | |
| SCHEMBL25191131 | 0.62 | MAP4K4 (0.48) | TRPV3KDM4EMAPTMAP4K4PDE10A | |
| SCHEMBL29218615 | 0.62 | MAP4K4 (0.45) | TRPV3KDM4EMAPTMAP4K4PDE10A | |
| SCHEMBL25039721 | 0.62 | TRPV3 (0.47) | TRPV3KDM4EMAPTMAP4K4PDE10A | |
| SCHEMBL25187824 | 0.62 | MAPT (0.47) | TRPV3KDM4EMAPTMAP4K4PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020055192-A2 | PREPARATION METHOD FOR QUINOLINE-5, 8-DIONE DERIVATIVE WHICH IS TGASE 2 INHIBITOR | 재단법인 대구경북첨단의료산업진흥재단 | 2020-03-19 | — | — | WO | disclosed |