SCHEMBL21801769

SCHEMBL21801769

O=C(O)c1ccccc1C(=O)OC[C@@H]1CO1

nearest known ligand 0.61

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.54
ALDH1A1 P00352 1/20 0.54
MAPK1 P28482 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
MGLL Q99685 5/20 0.51
TDP1 Q9NUW8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL529997 1.00 DHFR (0.54) DHFRALDH1A1MAPK1L3MBTL1MGLL
SCHEMBL30541879 1.00 DHFR (0.54) DHFRALDH1A1MAPK1L3MBTL1MGLL
Cyclohexane SCHEMBL28117089 0.97 DHFR (0.52) DHFRALDH1A1MAPK1L3MBTL1MGLL
SCHEMBL29374975 0.93 DHFR (0.59) DHFRALDH1A1MAPK1L3MBTL1MGLL
SCHEMBL121520 0.93 DHFR (0.59) DHFRALDH1A1MAPK1L3MBTL1MGLL
SCHEMBL21801767 0.93 DHFR (0.59) DHFRALDH1A1MAPK1L3MBTL1MGLL
Propene SCHEMBL9132191 0.92 DHFR (0.48) DHFRALDH1A1MAPK1L3MBTL1MGLL
Acrylic Acid SCHEMBL28214340 0.92 DHFR (0.48) DHFRALDH1A1MAPK1L3MBTL1MGLL
SCHEMBL27625461 0.89 MGLL (0.51) DHFRMAPK1L3MBTL1MGLL
SCHEMBL28387457 0.89 DHFR (0.55) DHFRMAPK1L3MBTL1MGLLTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020051967-A1 PREPARATION METHOD FOR (S)-GLYCIDYL PHTHALIMIDE 新发药业有限公司 2020-03-19 WO disclosed