Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21802036 | 1.00 | ALPL (0.47) | ALPLALDH1A1MAPK1HTTMEN1 | |
| SCHEMBL21801973 | 0.81 | ALPL (0.49) | ALPLMEN1NPC1RAB9AKMT2A | |
| SCHEMBL21802097 | 0.80 | ALPL (0.48) | ALPLALDH1A1MAPK1HTTOPRK1 | |
| SCHEMBL21802113 | 0.80 | ALPL (0.49) | ALPLALDH1A1MAPK1HTTIDO1 | |
| SCHEMBL30538731 | 0.80 | ALPL (0.48) | ALPLALDH1A1MAPK1HTTOPRK1 | |
| SCHEMBL21801956 | 0.80 | ALPL (0.49) | ALPLALDH1A1MAPK1HTTIDO1 | |
| SCHEMBL21802103 | 0.80 | ALPL (0.48) | ALPLALDH1A1MAPK1HTTIDO1 | |
| SCHEMBL21801957 | 0.80 | ALPL (0.49) | ALPLALDH1A1MAPK1HTTIDO1 | |
| SCHEMBL21801949 | 0.79 | ALPL (0.49) | ALPLALDH1A1MAPK1HTTIDO1 | |
| SCHEMBL4484613 | 0.79 | CHRNB4 (0.48) | ALDH1A1MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3559007-B1 | SULFONAMIDE COMPOUNDS HAVING TNAP INHIBITORY ACTIVITY | DAIICHI SANKYO CO LTD (JP) | 2023-08-16 | — | — | EP | disclosed |
| US-11046710-B2 | Sulfonamide compounds | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-06-29 | — | — | US | disclosed |
| US-11014939-B2 | — | — | 2021-05-25 | — | — | US | disclosed |
| US-20200087321-A1 | SULFONAMIDE COMPOUNDS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2020-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200087321-A1 | SULFONAMIDE COMPOUNDS | ALPI, ASAH2, STS | ALPL 7/4885ALDH1A1 310/4885MAPK1 2193/4885 |
| US-11014939-B2 | — | ALPI, ALPP, ACER2 | ALPL 5/4885ALDH1A1 177/4885MAPK1 2373/4885 |
| US-11046710-B2 | Sulfonamide compounds | ALPI, ASAH2, STS | ALPL 7/4885ALDH1A1 310/4885MAPK1 2193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.