Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1D | O15297 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15519418 | 0.89 | — | — | |
| SCHEMBL376274 | 0.89 | PPM1D (0.33) | PPM1D | |
| SCHEMBL4301879 | 0.89 | PPM1D (0.33) | PPM1D | |
| SCHEMBL3469089 | 0.89 | PPM1D (0.33) | PPM1D | |
| SCHEMBL3433762 | 0.89 | PPM1D (0.33) | PPM1D | |
| SCHEMBL4336670 | 0.89 | PPM1D (0.33) | PPM1D | |
| SCHEMBL4292430 | 0.87 | PPM1D (0.34) | PPM1D | |
| SCHEMBL2634064 | 0.86 | PPM1D (0.34) | PPM1D | |
| SCHEMBL3470472 | 0.86 | PPM1D (0.34) | PPM1D | |
| SCHEMBL5314317 | 0.86 | PPM1D (0.34) | PPM1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3559007-B1 | SULFONAMIDE COMPOUNDS HAVING TNAP INHIBITORY ACTIVITY | DAIICHI SANKYO CO LTD (JP) | 2023-08-16 | — | — | EP | disclosed |
| US-11046710-B2 | Sulfonamide compounds | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-06-29 | — | — | US | disclosed |
| US-11014939-B2 | — | — | 2021-05-25 | — | — | US | disclosed |
| US-20200087321-A1 | SULFONAMIDE COMPOUNDS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2020-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200087321-A1 | SULFONAMIDE COMPOUNDS | ALPI, ASAH2, STS | PPM1D 723/4885 |
| US-11014939-B2 | — | ALPI, ALPP, ACER2 | PPM1D 1385/4885 |
| US-11046710-B2 | Sulfonamide compounds | ALPI, ASAH2, STS | PPM1D 723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.