Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1D | O15297 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL376274 | 0.89 | PPM1D (0.33) | PPM1D | |
| SCHEMBL21802121 | 0.89 | PPM1D (0.33) | PPM1D | |
| SCHEMBL4301879 | 0.89 | PPM1D (0.33) | PPM1D | |
| SCHEMBL3469089 | 0.89 | PPM1D (0.33) | PPM1D | |
| SCHEMBL4336670 | 0.89 | PPM1D (0.33) | PPM1D | |
| SCHEMBL4725652 | 0.88 | BDKRB2 (0.34) | PPM1D | |
| SCHEMBL4292430 | 0.87 | PPM1D (0.34) | PPM1D | |
| SCHEMBL5314317 | 0.86 | PPM1D (0.34) | PPM1D | |
| SCHEMBL29245844 | 0.86 | PPM1D (0.34) | PPM1D | |
| SCHEMBL30729563 | 0.86 | PPM1D (0.34) | PPM1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252595-A1 | OXIM DERIVATIVES AS HSP90 INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009097578-A1 | OXIM DERIVATIVES AS HSP90 INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-08-06 | — | — | WO | disclosed |