Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21802540 | 0.86 | MGLL (0.48) | KCNJ1 | |
| SCHEMBL21802553 | 0.85 | MAPT (0.53) | KDM4EALDH1A1GAASMN1; SMN2MEN1 | |
| SCHEMBL15100777 | 0.84 | MGLL (0.66) | — | |
| SCHEMBL15265250 | 0.84 | MGLL (0.43) | KDM4EALDH1A1GAATDP1SMN1; SMN2 | |
| SCHEMBL21802541 | 0.82 | CYP2A13 (0.52) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15265357 | 0.82 | RORC (0.48) | ALDH1A1MEN1KMT2A | |
| SCHEMBL21802523 | 0.82 | MGLL (0.44) | ALDH1A1GAASMN1; SMN2HTR7POLB | |
| SCHEMBL21802528 | 0.80 | FAAH (0.56) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL13634389 | 0.79 | MEN1 (0.52) | KDM4EALDH1A1GAATDP1POLB | |
| SCHEMBL19086425 | 0.78 | KDM4E (0.61) | KDM4EALDH1A1GAATDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2800565-B1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | LUNDBECK LA JOLLA RESEARCH CENTER INC (US) | 2020-03-25 | — | — | EP | claimed |