Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20571132 | 0.91 | FAAH (0.65) | FAAHGRIN2BALDH1A1HTTMEN1 | |
| SCHEMBL15094215 | 0.84 | FAAH (0.48) | FAAHGRIN2BKMT2AMGLL | |
| SCHEMBL15265238 | 0.83 | FAAH (0.55) | FAAHGRIN2BALDH1A1KDM4EGAA | |
| SCHEMBL15263987 | 0.83 | ALDH1A1 (0.52) | FAAHGRIN2BALDH1A1HTTMEN1 | |
| SCHEMBL21868785 | 0.83 | ICMT (0.56) | FAAHGRIN2BALDH1A1HTT | |
| SCHEMBL21802519 | 0.82 | FAAH (0.53) | FAAHGRIN2BALDH1A1MEN1KMT2A | |
| SCHEMBL15264609 | 0.81 | FAAH (0.46) | FAAHGRIN2BALDH1A1HTTMEN1 | |
| SCHEMBL15265378 | 0.81 | ALDH1A1 (0.45) | FAAHGRIN2BALDH1A1HTTMEN1 | |
| SCHEMBL15265341 | 0.81 | FAAH (0.50) | FAAHGRIN2BALDH1A1HTTMEN1 | |
| SCHEMBL17276707 | 0.81 | FAAH (0.63) | FAAHGRIN2BALDH1A1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2800565-B1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | LUNDBECK LA JOLLA RESEARCH CENTER INC (US) | 2020-03-25 | — | — | EP | claimed |