Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL115415 | 1.00 | SLC6A4 (0.33) | SLC6A4SLC6A2SLC6A3DRD2TACR1 | |
| SCHEMBL14844322 | 1.00 | SLC6A4 (0.33) | SLC6A4SLC6A2SLC6A3DRD2TACR1 | |
| SCHEMBL2180437 | 0.89 | SLC6A4 (0.41) | SLC6A4SLC6A2SLC6A3TACR1KCNH2 | |
| SCHEMBL901681 | 0.89 | OPRM1 (0.40) | SLC6A4SLC6A2SLC6A3HTR2C | |
| SCHEMBL115890 | 0.85 | SLC6A2 (0.37) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL28205007 | 0.85 | SLC6A2 (0.37) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL18229253 | 0.85 | SLC6A2 (0.37) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2179928 | 0.84 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3TACR1KCNH2 | |
| SCHEMBL794941 | 0.83 | SLC6A2 (0.38) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2179695 | 0.79 | HTR2A (0.31) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3896058-A2 | ENANTIONSELECTIVE PROCESSES TO INSECTICIDAL 3-ARYL-3-TRIFLUOROMETHYL-SUBSTITUTED PYRROLIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-10-20 | — | — | EP | disclosed |
| EP-3896058-A2 | ENANTIONSELECTIVE PROCESSES TO INSECTICIDAL 3-ARYL-3-TRIFLUOROMETHYL-SUBSTITUTED PYRROLIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-10-20 | — | — | EP | disclosed |
| CN-109438316-A | The enantioselective process of the substituted pyrrolidines of the 3- aryl -3- trifluoromethyl-of desinsection | 先正达参股股份有限公司 | 2019-03-08 | — | — | CN | disclosed |
| CN-105017125-B | Enantioselective process for insecticidal 3-aryl-3-trifluoromethyl-substituted pyrrolidines | 先正达参股股份有限公司 | 2018-12-11 | — | — | CN | disclosed |
| US-9469633-B2 | Processes for the preparation of pyrrolidine intermediates | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-18 | — | — | US | disclosed |
| US-9469633-B2 | Processes for the preparation of pyrrolidine intermediates | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-18 | — | — | US | disclosed |
| US-9469633-B2 | Processes for the preparation of pyrrolidine intermediates | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-18 | — | — | US | disclosed |
| CN-105017125-A | Enantioselective process for insecticidal 3-aryl-3-trifluoromethyl-substituted pyrrolidines | SYNGENTA PARTICIPATIONS AG | 2015-11-04 | — | — | CN | disclosed |
| US-20140296527-A1 | PROCESSES FOR THE PREPARATION OF PYRROLIDINE INTERMEDIATES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-02 | — | — | US | disclosed |
| US-20140296527-A1 | PROCESSES FOR THE PREPARATION OF PYRROLIDINE INTERMEDIATES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-02 | — | — | US | disclosed |
| US-20140296527-A1 | PROCESSES FOR THE PREPARATION OF PYRROLIDINE INTERMEDIATES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-02 | — | — | US | disclosed |
| EP-2763963-A1 | ENANTIONSELECTIVE PROCESSES TO INSECTICIDAL 3-ARYL-3-TRIFLUOROMETHYL-SUBSTITUTED PYRROLIDINES | Syngenta Participations AG (CH) | 2014-08-13 | — | — | EP | disclosed |
| WO-2013050301-A1 | ENANTIONSELECTIVE PROCESSES TO INSECTICIDAL 3-ARYL-3-TRIFLUOROMETHYL-SUBSTITUTED PYRROLIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-04-11 | — | — | WO | disclosed |
| WO-2013050301-A1 | ENANTIONSELECTIVE PROCESSES TO INSECTICIDAL 3-ARYL-3-TRIFLUOROMETHYL-SUBSTITUTED PYRROLIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296527-A1 | PROCESSES FOR THE PREPARATION OF PYRROLIDINE INTERMEDIATES | PPOX, PRDX2, CBR1 | SLC6A4 4696/4885SLC6A2 4283/4885SLC6A3 4580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.