Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 19/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 19/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 19/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28205007 | 0.89 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3CYP2D6CYP1A2 | |
| SCHEMBL18229253 | 0.89 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3CYP2D6CYP1A2 | |
| SCHEMBL115890 | 0.89 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3CYP2D6CYP1A2 | |
| SCHEMBL115415 | 0.83 | SLC6A4 (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14844401 | 0.83 | SLC6A4 (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14844322 | 0.83 | SLC6A4 (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2180925 | 0.82 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL10279155 | 0.80 | PDK2 (0.35) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL794414 | 0.80 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL2180437 | 0.80 | SLC6A4 (0.41) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104603139-B | Spirocyclic derivatives as antiparasitic | 硕腾服务有限责任公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-104321317-B | Insecticidal arylpyrrolidines | 拜耳知识产权有限责任公司 | 2016-09-21 | — | — | CN | disclosed |
| US-9375000-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| US-9221835-B2 | Spirocyclic derivatives as antiparasitic agents | ZOETIS SERVICES LLC (US) | 2015-12-29 | — | — | US | disclosed |
| US-9221835-B2 | Spirocyclic derivatives as antiparasitic agents | ZOETIS SERVICES LLC (US) | 2015-12-29 | — | — | US | disclosed |
| US-9221835-B2 | Spirocyclic derivatives as antiparasitic agents | ZOETIS SERVICES LLC (US) | 2015-12-29 | — | — | US | disclosed |
| US-9206122-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-08 | — | — | US | disclosed |
| US-20150210710-A1 | SPIROCYCLIC DERIVATIVES AS ANTIPARASITIC AGENTS | ZOETIS SERVICES LLC | 2015-07-30 | — | — | US | disclosed |
| US-20150210710-A1 | SPIROCYCLIC DERIVATIVES AS ANTIPARASITIC AGENTS | ZOETIS SERVICES LLC | 2015-07-30 | — | — | US | disclosed |
| US-20150210710-A1 | SPIROCYCLIC DERIVATIVES AS ANTIPARASITIC AGENTS | ZOETIS SERVICES LLC | 2015-07-30 | — | — | US | disclosed |
| EP-2892902-A1 | SPIROCYCLIC DERIVATIVES AS ANTIPARASITIC AGENTS | Zoetis LLC (US) | 2015-07-15 | — | — | EP | disclosed |
| CN-103282347-B | Pesticidal arylpyrrolidines | BAYER IP GMBH | 2015-04-01 | — | — | CN | disclosed |
| US-20150025253-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-01-22 | — | — | US | disclosed |
| EP-2825532-A1 | PESTICIDAL ARYLPYRROLIDINES | Bayer Intellectual Property GmbH (DE) | 2015-01-21 | — | — | EP | disclosed |
| WO-2014039489-A1 | SPIROCYCLIC DERIVATIVES AS ANTIPARASITIC AGENTS | ZOETIS LLC (US) | 2014-03-13 | — | — | WO | disclosed |
| WO-2014039489-A1 | SPIROCYCLIC DERIVATIVES AS ANTIPARASITIC AGENTS | ZOETIS LLC (US) | 2014-03-13 | — | — | WO | disclosed |
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-02-13 | — | — | US | disclosed |
| WO-2013135724-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-09-19 | — | — | WO | disclosed |
| EP-2616437-A1 | PESTICIDAL ARYLPYRROLIDINES | Bayer Intellectual Property GmbH (DE) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035011-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150210710-A1 | SPIROCYCLIC DERIVATIVES AS ANTIPARASITIC AGENTS | AVPR1A, AVPR1B, AVPR2 | SLC6A2 1804/4885SLC6A4 3344/4885SLC6A3 1155/4885 |
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | DDT, ACHE, CAT | SLC6A2 2777/4885SLC6A4 2485/4885SLC6A3 2120/4885 |
| US-20150025253-A1 | PESTICIDAL ARYLPYRROLIDINES | DDT, ACHE, NPEPPS | SLC6A2 3529/4885SLC6A4 2886/4885SLC6A3 2550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.