SCHEMBL218054

SCHEMBL218054

NNc1ccc(NN)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.67
IDO1 P14902 4/20 0.67
LMNA P02545 2/20 0.67
PTGS2 P35354 2/20 0.67
CYP1A2 P05177 2/20 0.67
CYP3A4 P08684 2/20 0.67
CYP2C9 P11712 2/20 0.67
CYP2C19 P33261 2/20 0.67
CYP2D6 P10635 1/20 0.67
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
CA9 Q16790 2/20 0.55
CA12 O43570 1/20 0.55
CA4 P22748 1/20 0.55
CA6 P23280 1/20 0.55
CA5A P35218 1/20 0.55
CA7 P43166 1/20 0.55
CA14 Q9ULX7 1/20 0.55
CA5B Q9Y2D0 1/20 0.55
NOS1 P29475 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4852769 0.89 TDP1 (0.56) TDP1IDO1LMNAPTGS2CYP1A2
SCHEMBL4094372 0.89 TDP1 (0.56) TDP1IDO1LMNAPTGS2CYP1A2
Hydrochloric Acid SCHEMBL31628644 0.86 TDP1 (0.53) TDP1IDO1LMNAPTGS2CYP1A2
SCHEMBL1709616 0.86
SCHEMBL8096 0.83
SCHEMBL11476899 0.83 CYP3A4 (0.50) TDP1IDO1LMNAPTGS2CYP1A2
SCHEMBL7151 0.83
SCHEMBL7843 0.83
SCHEMBL5798730 0.83
SCHEMBL2136520 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2246403-A1 Waterborne adhesive formulations Akzo Nobel Coatings International B.V. (NL) 2010-11-03 EP claimed
US-20260109086-A1 METHOD OF FORMING A BONDED STRUCTURE LOCKHEED CORP (US) 2026-04-23 US disclosed
EP-4377368-B1 AQUEOUS POLYURETHANE DISPERSION ALLNEX AUSTRIA GMBH (AT) 2025-06-18 EP disclosed
US-20250001647-A1 RESIN INFUSED PI-SHAPED PREFORM AND JOINTS THEREOF LOCKHEED CORP (US) 2025-01-02 US disclosed
US-20240352178-A1 AQUEOUS POLYURETHANE DISPERSION ALLNEX AUSTRIA GMBH (AT) 2024-10-24 US disclosed
EP-4400523-A1 AQUEOUS POLYURETHANE-VINYL POLYMER HYBRID DISPERSION Allnex Austria GmbH (AT) 2024-07-17 EP disclosed
CN-117642443-A Aqueous polyurethane dispersions 湛新奥地利有限公司 2024-03-01 CN disclosed
US-20230374192-A1 AQUEOUS SELF-CROSSLINKABLE POLYURETHANE DISPERSIONS BASF SE (DE) 2023-11-23 US disclosed
CN-117062873-A Polyacetal resin composition and method for producing same 旭化成株式会社 2023-11-14 CN disclosed
EP-4217410-A1 AQUEOUS SELF-CROSSLINKABLE POLYURETHANE DISPERSIONS BASF SE (DE) 2023-08-02 EP disclosed
US-4250070-A ALSO CONTAINING HEAVY METAL IONS; STORAGE STABILITY; CROSSLINKING; COATINGS BASF AKTIENGESELLSCHAFT (DE) 1981-02-10 US disclosed
US-4247474-A POLYFUNCTIONAL ALKYLENE, CYCLOALKYLENE, OR ARYLENE DERIVATIVES; HYDROGEN CHLORIDE SALTS USED AS CURING AGENTS HERCULES INCORPORATED (US) 1981-01-27 US disclosed
EP-0003516-A1 Aquous dispersions of copolymers with carbonyl groups that contain hydrazine derivatives and heavy metal ions BASF Aktiengesellschaft (DE) 1979-08-22 EP disclosed
US-4097651-A Substrates coated with end and intermediate reaction products of a dianhydride and a hydrazine or hydrazide PPG INDUSTRIES, INC. (US) 1978-06-27 US disclosed
US-4089846-A Polysalts of acid-ester compounds with hydrazine or hydrazides and method of preparing heterocyclic polymers from said polysalts PPG INDUSTRIES, INC. (US) 1978-05-16 US disclosed
US-4075240-A Polysalts of polycarboxylic acid esters and hydrazine or hydrazides PPG INDUSTRIES, INC (US) 1978-02-21 US disclosed
US-4049637-A Polymer prepared from hydrazine and tricarboxylic acid derivatives and method of preparation PPG INDUSTRIES, INC. (US) 1977-09-20 US disclosed
US-4046949-A Novel polymers from reaction of tricarboxylic anhydrides and hydrazines or hydrazides coated on substrate PPG INDUSTRIES, INC. (US) 1977-09-06 US disclosed
US-4020050-A Method of preparing polymer from dianhydride and hydrazine or dihydrazide PPG INDUSTRIES, INC. (US) 1977-04-26 US disclosed
US-3969566-A Articles of manufacturing prepared from polymers of hydrazine or dihydrazides and tricarboxylic acid anhydrides PPG INDUSTRIES, INC. (US) 1976-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109086-A1 METHOD OF FORMING A BONDED STRUCTURE CDH1, COL2A1, COL1A1 TDP1 1869/4885IDO1 3663/4885LMNA 312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.