SCHEMBL21805908

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22289031	0.86	LMNA (0.47)	MCL1BAK1ALDH1A1MEN1KMT2A
	SCHEMBL31159061	0.83	MCL1 (0.64)	FOLH1MCL1BAK1ALKBH1ALDH1A1
	SCHEMBL31727623	0.83	MCL1 (0.64)	FOLH1MCL1BAK1ALKBH1ALDH1A1
	SCHEMBL27827736	0.82	NOX1 (0.56)	FOLH1MCL1BAK1ALKBH1ALDH1A1
	SCHEMBL31388800	0.82	MCL1 (0.53)	FOLH1MCL1BAK1ALKBH1ALDH1A1
	SCHEMBL1680784	0.80	MAPT (0.50)	ALDH1A1NAPRT
	SCHEMBL29424833	0.79	LTA4H (0.49)	CDK1CCNB1MGMTCCNA2CDK2
	SCHEMBL2191517	0.79	LTA4H (0.49)	CDK1CCNB1MGMTCCNA2CDK2
	SCHEMBL19329183	0.78	MCL1 (0.59)	FOLH1MCL1BAK1ALKBH1GRM5
	SCHEMBL1680324	0.78	NAPRT (0.42)	FOLH1ALDH1A1NAPRTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.