Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31405356 | 0.84 | ARG1 (0.37) | NAAATDP1ALOX5EPHX1 | |
| SCHEMBL27812725 | 0.75 | TDP1 (0.39) | NAAATDP1ALOX5 | |
| Water SCHEMBL28036000 | 0.74 | EPHX1 (0.35) | NAAATDP1EPHX1 | |
| SCHEMBL28023532 | 0.74 | ALOX5 (0.41) | TDP1ALOX5 | |
| Sulfuric Acid SCHEMBL8607900 | 0.74 | NAAA (0.36) | NAAATDP1EPHX1EPHX2 | |
| SCHEMBL24925663 | 0.74 | TDP1 (0.40) | TDP1EPHX1 | |
| SCHEMBL10706271 | 0.74 | EPHX1 (0.37) | NAAATDP1EPHX1 | |
| SCHEMBL31314377 | 0.74 | CYP1A2 (0.41) | NAAATDP1EPHX1EPHX2 | |
| SCHEMBL28169087 | 0.73 | CYP1A2 (0.39) | TDP1EPHX1 | |
| Water SCHEMBL28822891 | 0.72 | TDP1 (0.36) | NAAATDP1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110637015-B | Fanisole X receptor agonist and application thereof | 奥加诺沃公司 | 2024-04-02 | — | — | CN | disclosed |
| EP-3596053-B1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | ORGANOVO INC (US) | 2023-08-16 | — | — | EP | disclosed |
| EP-3852736-A1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | Metacrine, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |
| WO-2020061118-A1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | METACRINE, INC. (US) | 2020-03-26 | — | — | WO | disclosed |
| WO-2020061116-A1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | METACRINE, INC. (US) | 2020-03-26 | — | — | WO | disclosed |
| WO-2020061117-A1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | METACRINE, INC. (US) | 2020-03-26 | — | — | WO | disclosed |