Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21909542 | 0.90 | MAOB (0.45) | MAOBKMT2AMAOACA12CA1 | |
| SCHEMBL21806302 | 0.90 | MAOB (0.52) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL21806750 | 0.88 | BCHE (0.43) | MAOBKMT2AMAOACA12CA1 | |
| SCHEMBL21806190 | 0.87 | MAOB (0.42) | MAOBKMT2AMAOACA12CA1 | |
| Trifluoroacetic Acid SCHEMBL21806629 | 0.85 | AKR1B10 (0.49) | MAOBCA12CA1CA2CA4 | |
| Trifluoroacetic Acid SCHEMBL21806084 | 0.85 | MAOB (0.48) | MAOBMAOACA12CA1CA2 | |
| SCHEMBL21806200 | 0.85 | CA12 (0.43) | MAOBKMT2AMAOACA12CA1 | |
| SCHEMBL21806631 | 0.85 | CA12 (0.47) | MAOBCA12CA1CA2CA4 | |
| SCHEMBL24012358 | 0.84 | MAOB (0.39) | MAOBKMT2AMAOACA12CA1 | |
| SCHEMBL21806085 | 0.81 | MAOB (0.44) | MAOBMAOACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3853214-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | Ventana Medical Systems, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |
| WO-2020058339-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | VENTANA MEDICAL SYSTEMS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |
| WO-2020058339-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | VENTANA MEDICAL SYSTEMS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |