Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 10/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 9/20 | 0.49 |
| ▸ | AKR1A1 | P14550 | 2/20 | 0.47 |
| ▸ | CBR1 | P16152 | 2/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA4 | P22748 | 3/20 | 0.46 |
| ▸ | CA5A | P35218 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21806631 | 0.93 | CA12 (0.47) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL21806210 | 0.85 | MAOB (0.46) | AKR1B10AKR1B1CA12CA1CA2 | |
| Trifluoroacetic Acid SCHEMBL21806084 | 0.83 | MAOB (0.48) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL25279702 | 0.81 | AKR1B10 (0.75) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL25708668 | 0.80 | AKR1B10 (0.77) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL25235579 | 0.79 | AKR1B10 (0.64) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL21806302 | 0.79 | MAOB (0.52) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL28636411 | 0.79 | CA12 (0.44) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL21806177 | 0.78 | AKR1B10 (0.41) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL21806085 | 0.77 | MAOB (0.44) | AKR1B10AKR1B1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3853214-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | Ventana Medical Systems, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |
| WO-2020058339-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | VENTANA MEDICAL SYSTEMS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |