Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL21806084 | 0.88 | MAOB (0.48) | MAOBALDH1A1AKR1B10AKR1B1MAOA | |
| SCHEMBL21806302 | 0.87 | MAOB (0.52) | MAOBALDH1A1AKR1B10AKR1B1MAOA | |
| SCHEMBL21806631 | 0.81 | CA12 (0.47) | MAOBAKR1B10AKR1B1NPC1CA12 | |
| SCHEMBL21806210 | 0.81 | MAOB (0.46) | MAOBALDH1A1KDM4EAKR1B10AKR1B1 | |
| SCHEMBL21806222 | 0.79 | ALDH1A1 (0.48) | MAOBALDH1A1KDM4ETP53GLA | |
| Trifluoroacetic Acid SCHEMBL21806629 | 0.77 | AKR1B10 (0.49) | MAOBAKR1B10AKR1B1NPC1CA12 | |
| SCHEMBL21806139 | 0.76 | MAOB (0.48) | MAOBALDH1A1KDM4ETP53GLA | |
| SCHEMBL21806218 | 0.72 | MAOB (0.45) | MAOBALDH1A1AKR1B10AKR1B1MAOA | |
| SCHEMBL21909542 | 0.71 | MAOB (0.45) | MAOBALDH1A1KDM4EAKR1B10AKR1B1 | |
| SCHEMBL24012380 | 0.69 | MAOB (0.50) | MAOBALDH1A1KDM4ETP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210349101-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | VENTANA MEDICAL SYSTEMS, INC. | 2021-11-11 | — | — | US | disclosed |
| EP-3853214-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | Ventana Medical Systems, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |
| WO-2020058339-A1 | COUMARIN-BASED CROSSLINKING REAGENTS | VENTANA MEDICAL SYSTEMS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |