Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | MTOR | P42345 | 1/20 | 0.70 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.70 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.70 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.57 |
| ▸ | ST6GAL1 | P15907 | 6/20 | 0.55 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3272277 | 0.89 | LMNA (0.76) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL1896533 | 0.88 | LMNA (0.70) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL12988159 | 0.88 | LMNA (0.70) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL9856687 | 0.88 | LMNA (0.70) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL1139038 | 0.87 | LMNA (0.72) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL7775031 | 0.87 | LMNA (0.69) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL366600 | 0.87 | LMNA (0.75) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL5491562 | 0.87 | LMNA (0.75) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL4946508 | 0.87 | LMNA (0.75) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL11588979 | 0.87 | LMNA (0.79) | LMNATHRBMTORMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079501-A1 | PRODRUG BASED ON CYTARABINE STRUCTURE AS WELL AS SYNTHESIZING METHOD AND APPLICATION THEREOF | 济南圣鲁金药物技术开发有限公司 (CN) | 2011-07-07 | — | — | WO | disclosed |