SCHEMBL366600

SCHEMBL366600

Nc1ccn([C@@H]2O[C@H](COO)[C@@H](O)[C@H]2O)c(=O)n1

nearest known ligand 0.75

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.75
THRB P10828 1/20 0.75
MTOR P42345 1/20 0.75
MDM2 Q00987 1/20 0.75
NCOA1 Q15788 1/20 0.75
NCOA3 Q9Y6Q9 1/20 0.75
L3MBTL1 Q9Y468 1/20 0.61
TSHR P16473 1/20 0.60
GLA P06280 1/20 0.60
P2RY2 P41231 1/20 0.60
ST6GAL1 P15907 5/20 0.57
NT5E P21589 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9010747 0.90 LMNA (0.72) LMNATHRBMTORMDM2NCOA1
SCHEMBL5491562 0.90 LMNA (0.75) LMNATHRBMTORMDM2NCOA1
SCHEMBL4946508 0.90 LMNA (0.75) LMNATHRBMTORMDM2NCOA1
SCHEMBL14178411 0.89 LMNA (0.73) LMNATHRBMTORMDM2NCOA1
SCHEMBL2811458 0.89 LMNA (0.73) LMNATHRBMTORMDM2NCOA1
SCHEMBL13524621 0.89 LMNA (0.73) LMNATHRBMTORMDM2NCOA1
SCHEMBL383499 0.89 LMNA (0.73) LMNATHRBMTORMDM2NCOA1
SCHEMBL17304691 0.89 LMNA (0.73) LMNATHRBMTORMDM2NCOA1
SCHEMBL18231346 0.89 LMNA (0.73) LMNATHRBMTORMDM2NCOA1
SCHEMBL15338532 0.89 LMNA (0.73) LMNATHRBMTORMDM2NCOA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024144420-A1 USE OF 5'-О-(3-PHENYLPROPIONYL)-N4-HYDROXYCYTIDINE TO INHIBIT INFLUENZA VIRUS REPLICATION IN VITRO AND IN VIVO федеральное государственное бюджетное учреждение "Национальный исследовательский центр эпидемиологии и микробиологии имени почетного академика Н.Ф. Гамалеи" Министерства здравоохранения Российской Федерации 2024-07-04 WO claimed
WO-2024129551-A1 SOLID DOSAGE FORM OF A SMALL MOLECULE ANTIVIRAL AND USES THEREOF MERCK SHARP & DOHME LLC (US) 2024-06-20 WO claimed
EP-4380578-A1 METHOD OF TREATING VETERINARY VIRAL DISEASES Intervet International B.V. (NL) 2024-06-12 EP claimed
EP-4319763-A2 MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES Emory University (US) 2024-02-14 EP claimed
EP-4319764-A2 THIONUCLEOSIDES AS ANTIVIRAL AGENTS Emory University (US) 2024-02-14 EP claimed
EP-4319762-A2 NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS Emory University (US) 2024-02-14 EP claimed
US-20240041828-A1 Combination Therapeutics Comprising Nrf2 Agonists and Antivirals for Treating Viral Infections THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-02-08 US claimed
US-20230193231-A1 ENGINEERED GENE-EDITING PROTEINS FACTOR BIOSCIENCE INC. 2023-06-22 US claimed
EP-4149252-A2 ENGINEERED GENE-EDITING PROTEINS Factor Bioscience Inc. (US) 2023-03-22 EP claimed
EP-4142744-A1 MESENCHYMAL STEM CELL THERAPIES Factor Bioscience Inc. (US) 2023-03-08 EP claimed
CN-115768474-A Methods for treating COVID-19 related disorders 里格尔药品股份有限公司 2023-03-07 CN claimed
WO-2023012329-A1 METHOD OF TREATING VETERINARY VIRAL DISEASES INTERVET INTERNATIONAL B.V. (NL) 2023-02-09 WO claimed
WO-2022217155-A2 THIONUCLEOSIDES AS ANTIVIRAL AGENTS EMORY UNIVERSITY (US) 2022-10-13 WO claimed
WO-2022212914-A1 METHODS OF TREATING VIRAL DISEASES AMPIO PHARMACEUTICALS, INC. (US) 2022-10-06 WO claimed
WO-2021231549-A2 ENGINEERED GENE-EDITING PROTEINS FACTOR BIOSCIENCE INC. (US) 2021-11-18 WO claimed
WO-2021222389-A1 MESENCHYMAL STEM CELL THERAPIES FACTOR BIOSCIENCE INC. (US) 2021-11-04 WO claimed
EP-1725266-A4 POTENT MUCOSAL IMMUNE RESPONSE INDUCED BY MODIFIED IMMUNOMODULATORY OLIGONUCLEOTIDES HYBRIDON INC (US) 2008-05-07 EP claimed
EP-1725266-A2 POTENT MUCOSAL IMMUNE RESPONSE INDUCED BY MODIFIED IMMUNOMODULATORY OLIGONUCLEOTIDES HYBRIDON, INC. (US) 2006-11-29 EP claimed
WO-2005081847-A2 POTENT MUCOSAL IMMUNE RESPONSE INDUCED BY MODIFIED IMMUNOMODULATORY OLIGONUCLEOTIDES HYBRIDON, INC. (US) 2005-09-09 WO claimed
WO-2003035836-A2 MODULATION OF IMMUNOSTIMULATORY PROPERTIES OF OLIGONUCLEOTIDE-BASED COMPOUNDS BY OPTIMAL PRESENTATION OF 5' ENDS HYBRIDON INC. (US) 2003-05-01 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240041828-A1 Combination Therapeutics Comprising Nrf2 Agonists and Antivirals for Treating Viral Infections KEAP1, HMOX1, NFE2L2 LMNA 2186/4885THRB 2846/4885MTOR 3008/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.