Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.54 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | HAVCR2 | Q8TDQ0 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3303841 | 0.79 | AHR (0.58) | AHRCYP11B2NUDT1PDE10A | |
| SCHEMBL258972 | 0.79 | EGLN2 (0.50) | EGLN2CYP11B2PDE10ANPC1RAB9A | |
| SCHEMBL13457590 | 0.78 | AHR (0.56) | AHRCYP11B2NUDT1 | |
| SCHEMBL20265119 | 0.77 | AHR (0.47) | AHREGLN2CYP11B2HPGDNUDT1 | |
| SCHEMBL28530395 | 0.76 | AHR (0.54) | AHRCYP11B2NUDT1 | |
| SCHEMBL45713 | 0.76 | NUDT1 (0.56) | AHREGLN2CYP11B2NUDT1PDE10A | |
| SCHEMBL543601 | 0.76 | EGLN2 (0.47) | AHREGLN2CYP11B2NUDT1TP53 | |
| SCHEMBL16439318 | 0.76 | AHR (0.50) | AHREGLN2CYP11B2 | |
| SCHEMBL19659205 | 0.73 | EGLN2 (0.45) | EGLN2CYP11B2NUDT1TP53PDE10A | |
| SCHEMBL19658704 | 0.73 | EGLN2 (0.45) | EGLN2CYP11B2NUDT1PDE10ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3852790-A1 | INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 9X | Forma Therapeutics, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |
| WO-2020061261-A1 | INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 9X | FORMA THERAPEUTICS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |