Aprobarbital

Aprobarbital

SCHEMBL21807710

C=CCC1(C(C)C)C(=O)NC(=O)NC1=O.[NaH]

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MMP9 P14780 1/20 0.65
CYP3A4 P08684 2/20 0.42
NR1I2 O75469 1/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
GABRB3 P28472 1/20 0.42
OPRD1 P41143 1/20 0.42
GABRA2 P47869 1/20 0.42
GABRB2 P47870 1/20 0.42
LMNA P02545 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aprobarbital SCHEMBL78101 0.98 MMP9 (0.67) MMP9CYP3A4NR1I2KDM4EALDH1A1
Talbutal SCHEMBL4263344 0.88 MMP9 (0.69) MMP9CYP3A4NR1I2KDM4EALDH1A1
SCHEMBL10582779 0.85 MMP9 (0.51) MMP9CYP3A4NR1I2KDM4EALDH1A1
Aprobarbital SCHEMBL15543386 0.83 MMP9 (0.51) MMP9CYP3A4NR1I2KDM4EALDH1A1
Talbutal SCHEMBL122147 0.81 MMP9 (0.76) MMP9CYP3A4NR1I2KDM4EALDH1A1
Secobarbital SCHEMBL614906 0.81 MMP9 (0.97) MMP9CYP3A4NR1I2KDM4EALDH1A1
Secobarbital SCHEMBL7599361 0.81 MMP9 (0.97) MMP9CYP3A4NR1I2KDM4EALDH1A1
Secobarbital SCHEMBL41182 0.81 MMP9 (0.97) MMP9CYP3A4NR1I2KDM4EALDH1A1
Secobarbital SCHEMBL8085730 0.79 MMP9 (1.00) MMP9CYP3A4NR1I2KDM4EALDH1A1
Secobarbital SCHEMBL80734 0.79 MMP9 (1.00) MMP9CYP3A4NR1I2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024073025-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2024-04-04 WO disclosed
EP-4344552-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2024-04-03 EP disclosed
US-20210346385-A1 TASTE-MASKED DOSAGE FORMS DEEP OCEAN CAPITAL MANAGEMENT LP 2021-11-11 US disclosed
WO-2020061584-A1 TASTE-MASKED DOSAGE FORMS MSB HOLDINGS, INC. (US) 2020-03-26 WO disclosed