SCHEMBL2180860

SCHEMBL2180860

CCSCCOP(O)(O)=S

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
LPAR3 Q9UBY5 15/20 0.48
LPAR2 Q9HBW0 13/20 0.48
ALDH1A1 P00352 1/20 0.45
CYP3A4 P08684 1/20 0.45
HSD17B10 Q99714 1/20 0.45
LPAR1 Q92633 9/20 0.40
LPAR6 P43657 3/20 0.33
LPAR4 Q99677 3/20 0.33
LPAR5 Q9H1C0 3/20 0.33
MVD P53602 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1202635 0.83 MEN1 (0.57) MEN1KMT2ATDP1LPAR3LPAR2
SCHEMBL118720 0.76 MEN1 (0.70) MEN1KMT2ATDP1ALDH1A1CYP3A4
SCHEMBL11446189 0.76 MEN1 (0.70) MEN1KMT2ATDP1ALDH1A1CYP3A4
SCHEMBL119049 0.76 TDP1 (1.00) MEN1KMT2ATDP1ALDH1A1CYP3A4
SCHEMBL6739006 0.76 MEN1 (0.70) MEN1KMT2ATDP1ALDH1A1CYP3A4
SCHEMBL10696687 0.75 MEN1 (0.48) MEN1KMT2ATDP1LPAR3LPAR2
SCHEMBL3486879 0.74 MEN1 (0.47) MEN1KMT2ATDP1LPAR3LPAR2
SCHEMBL28230751 0.72 MEN1 (0.46) MEN1KMT2ATDP1ALDH1A1CYP3A4
SCHEMBL899753 0.72
SCHEMBL11440601 0.71 ALDH1A1 (0.69) MEN1KMT2ATDP1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0268926-A2 Safened sorptive granular pesticidal resin compositions for controlling soil borne pests and process for the preparation thereof AMERICAN CYANAMID COMPANY (US) 1988-06-01 EP claimed
EP-0268927-A2 Resin-coated, non-sorptive granular, pesticidal compositions and method for the preparation thereof AMERICAN CYANAMID COMPANY (US) 1988-06-01 EP claimed
CN-110831584-B Targeted drug rescue with novel compositions, combinations and methods thereof 埃克塞瓦有限责任公司 2023-03-10 CN disclosed
EP-3349891-B1 METHOD FOR PREPARING MICROCAPSULES BY DOUBLE EMULSION CALYXIA (FR) 2021-04-21 EP disclosed
US-10807060-B2 Method for preparing microcapsules by double emulsion CALYXIA (FR) 2020-10-20 US disclosed
US-20200069674-A1 TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF Exciva GmbH (DE) 2020-03-05 US disclosed
CN-110831584-A Targeted drug rescue with novel compositions, combinations and methods thereof 埃克塞瓦有限责任公司 2020-02-21 CN disclosed
US-20180185809-A1 METHOD FOR PREPARING MICROCAPSULES BY DOUBLE EMULSION CALYXIA (FR) 2018-07-05 US disclosed
EP-3144058-A1 METHOD FOR PREPARING MICROCAPSULES BY DOUBLE EMULSION Calyxia (FR) 2017-03-22 EP disclosed
US-20140162906-A1 Pesticide Biomarker NAGY JON OWEN (US) 2014-06-12 US disclosed
US-20130137625-A1 Photo-Responsive Microencapsulation Materials, Compositions and Methods of Use Thereof SOLARBRE, INC. (US) 2013-05-30 US disclosed
US-4307115-A METHOMYL, STARCH AND AN ANTICAKING AGENT E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-12-22 US disclosed
US-4220663-A Combating pests with benzyl phenyl ethers BAYER AKTIENGESELLSCHAFT (DE) 1980-09-02 US disclosed
US-4174445-A INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-11-13 US disclosed
US-4145439-A NEMATOCIDES, FUNGICIDES, BACTERICIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-03-20 US disclosed
US-4067972-A PESTICIDES CIBA-GEIGY CORPORATION (US) 1978-01-10 US disclosed
US-4048315-A NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DT) 1977-09-13 US disclosed
US-3980799-A OR ACARICIDALLY ACTIVE SUBSTANCES CIBA-GEIGY AG (CH) 1976-09-14 US disclosed
US-3969444-A PESTICIDE CIBA-GEIGY AG (CH) 1976-07-13 US disclosed
US-3969438-A PESTICIDE CIBA-GEIGY AG (CH) 1976-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200069674-A1 TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF HTR2A, HTR2C, CYP3A43 MEN1 3248/4885KMT2A 1669/4885TDP1 760/4885
US-20130137625-A1 Photo-Responsive Microencapsulation Materials, Compositions and Methods of Use Thereof LIPA, LIPE, CRYAA MEN1 4057/4885KMT2A 4749/4885TDP1 3305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.