Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MASP2 | O00187 | 1/20 | 0.37 |
| ▸ | GAPDH | P04406 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21808869 | 0.86 | CYP1A2 (0.44) | CYP1A2ALDH1A1MEN1KMT2AGABRA1 | |
| SCHEMBL5561358 | 0.78 | CYP1A2 (0.49) | CYP1A2ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL3962062 | 0.76 | MDM4 (0.38) | MDM4ALDH1A1HSD17B10KDM4EMASP2 | |
| SCHEMBL13721486 | 0.75 | KMT2A (0.43) | CYP1A2ALDH1A1CYP2C9CYP2C19KMT2A | |
| SCHEMBL7076035 | 0.75 | LMNA (0.41) | CYP1A2DHFRLMNAALDH1A1MEN1 | |
| SCHEMBL12086776 | 0.74 | SIGMAR1 (0.50) | — | |
| SCHEMBL21808881 | 0.72 | KMT2A (0.43) | LMNAALDH1A1KMT2AKDM4EPOLB | |
| SCHEMBL27718829 | 0.71 | LMNA (0.38) | CYP1A2LMNAALDH1A1MEN1CYP2C9 | |
| SCHEMBL13931114 | 0.71 | CYP1A2 (0.41) | CYP1A2LMNAALDH1A1MEN1CYP2C9 | |
| SCHEMBL21808887 | 0.70 | KMT2A (0.43) | CYP1A2LMNAALDH1A1MEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3636642-B1 | INDOLEACETIC ACID DERIVATIVES FOR USE IN THE TREATMENT OF COUGH | INST CHINESE MATERIA MEDICA CHINA ACADEMY OF CMS (CN) | 2025-12-24 | — | — | EP | disclosed |
| US-11008360-B2 | Indoleacetic acid derivative and preparation method and pharmaceutical use thereof | INSTITUTE OF CHINESE MATERIA MEDICA, CHINA ACADEMY OF CHINESE MEDICAL SCIENCES (CN) | 2021-05-18 | — | — | US | disclosed |
| US-11008360-B2 | Indoleacetic acid derivative and preparation method and pharmaceutical use thereof | INSTITUTE OF CHINESE MATERIA MEDICA, CHINA ACADEMY OF CHINESE MEDICAL SCIENCES (CN) | 2021-05-18 | — | — | US | disclosed |
| EP-3636642-A1 | INDOLEACETIC ACID DERIVATIVE AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | Institute Of Chinese Materia Medica China Academy of Sciences (CN) | 2020-04-15 | — | — | EP | disclosed |
| US-20200095271-A1 | INDOLEACETIC ACID DERIVATIVE AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | INSTITUTE OF CHINESE MATERIA MEDICA, CHINA ACADEMY OF CHINESE MEDICAL SCIENCES (CN) | 2020-03-26 | — | — | US | disclosed |
| US-20200095271-A1 | INDOLEACETIC ACID DERIVATIVE AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | INSTITUTE OF CHINESE MATERIA MEDICA, CHINA ACADEMY OF CHINESE MEDICAL SCIENCES (CN) | 2020-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200095271-A1 | INDOLEACETIC ACID DERIVATIVE AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | IDO1, IDO2, TPH1 | CYP1A2 96/4885DHFR 1532/4885LMNA 3773/4885 |
| US-11008360-B2 | Indoleacetic acid derivative and preparation method and pharmaceutical use thereof | IDO1, IDO2, TPH1 | CYP1A2 96/4885DHFR 1532/4885LMNA 3773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.