SCHEMBL218111

SCHEMBL218111

CN(C)C=Nc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.53
KDM4E B2RXH2 6/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
GLA P06280 2/20 0.53
KMT2A Q03164 5/20 0.50
SMN1; SMN2 Q16637 4/20 0.49
HSD17B10 Q99714 3/20 0.49
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
GAA P10253 3/20 0.49
TP53 P04637 2/20 0.49
HPGD P15428 2/20 0.49
CYP1A2 P05177 2/20 0.49
CYP2C19 P33261 2/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
NFKB1 P19838 1/20 0.49
CASP1 P29466 1/20 0.49
CASP7 P55210 1/20 0.49
NFKB2 Q00653 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL218110 1.00 ALDH1A1 (0.53) ALDH1A1KDM4EL3MBTL1GLAKMT2A
SCHEMBL17761949 1.00 ALDH1A1 (0.53) ALDH1A1KDM4EL3MBTL1GLAKMT2A
SCHEMBL11882749 0.85 ALDH1A1 (0.53) ALDH1A1KDM4EL3MBTL1GLAKMT2A
SCHEMBL11882756 0.85 ALDH1A1 (0.53) ALDH1A1KDM4EL3MBTL1GLAKMT2A
SCHEMBL11260720 0.83 ALDH1A1 (0.62) ALDH1A1KDM4EL3MBTL1GLAKMT2A
SCHEMBL11260719 0.83 ALDH1A1 (0.62) ALDH1A1KDM4EL3MBTL1GLAKMT2A
SCHEMBL13404812 0.82 ALDH1A1 (0.43) ALDH1A1KDM4EL3MBTL1GLAKMT2A
SCHEMBL23422541 0.79 ALDH1A1 (0.53) ALDH1A1KDM4EL3MBTL1GLAKMT2A
SCHEMBL28667958 0.79 ALDH1A1 (0.53) ALDH1A1KDM4EL3MBTL1GLAKMT2A
SCHEMBL17828618 0.78 ALDH1A1 (0.55) ALDH1A1KDM4EL3MBTL1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559586-B2 Compositions containing uretdione groups crosslinking at low temperatures COVESTRO DEUTSCHLAND AG (DE) 2026-02-24 US disclosed
CN-115605525-B Uretdione-containing compositions that crosslink at low temperatures 科思创德国股份有限公司 2025-01-10 CN disclosed
EP-4157912-B1 COMPOSITIONS CONTAINING URETDIONE GROUPS CROSSLINKING AT LOW TEMPERATURES COVESTRO DEUTSCHLAND AG (DE) 2024-05-22 EP disclosed
US-20230192941-A1 COMPOSITIONS CONTAINING URETDIONE GROUPS CROSSLINKING AT LOW TEMPERATURES COVESTRO DEUTSCHLAND AG (DE) 2023-06-22 US disclosed
EP-4157912-A1 COMPOSITIONS CONTAINING URETDIONE GROUPS CROSSLINKING AT LOW TEMPERATURES Covestro Deutschland AG (DE) 2023-04-05 EP disclosed
WO-2022129138-A1 NON-IONIC HYDROPHILIZED POLYISOCYANATES, CATALYSIS WITH ZINC COMPLEXES COVESTRO DEUTSCHLAND AG (DE) 2022-06-23 WO disclosed
EP-4015547-A1 NONIONICALLY HYDROPHILICIZED POLYISOCYANATES, CATALYSIS WITH ZINC COMPLEXES Covestro Deutschland AG (DE) 2022-06-22 EP disclosed
EP-3362499-B1 SYSTEMS AND METHODS FOR FORMING POLYURETHANES EASTMAN CHEM CO (US) 2021-09-22 EP disclosed
US-20210024679-A1 CATALYST SYSTEM FOR URETDIONE DISPERSIONS COVESTRO DEUTSCHLAND AG (DE) 2021-01-28 US disclosed
EP-3543270-A1 CATALYST SYSTEM FOR URETDION DISPERSIONS Covestro Deutschland AG (DE) 2019-09-25 EP disclosed
US-6060574-A Reactive compositions containing blocked polyisocyanates and amine-functional resins BAYER AKTIENGESELLSCHAFT (DE) 2000-05-09 US disclosed
EP-0950675-A1 Reactive systems and their use for the production of coatings, adhesives, sealants, castings or mouldings BAYER AG (DE) 1999-10-20 EP disclosed
US-5847044-A Polyurethane powder coating compositions which have a low stoving temperature BAYER AKTIENGESELLSCHAFT (DE) 1998-12-08 US disclosed
EP-0803524-A1 Pulverulent polyurethane lacquer not releasing any decomposition products and having a lower baking temperature BAYER AG (DE) 1997-10-29 EP disclosed
US-5308735-A Aromatic-aldehyde resins, improved solubility NIPPON PAINT CO., LTD. (JP) 1994-05-03 US disclosed
EP-0540016-A1 Photosensitive resin and resin composition for lithographic printing Nippon Paint Co., Ltd. (JP) 1993-05-05 EP disclosed
US-4448975-A Process for the preparation of substituted amidines GENERAL ELECTRIC COMPANY (US) 1984-05-15 US disclosed
US-4353830-A Process for the preparation of substituted amidines GENERAL ELECTRIC COMPANY (US) 1982-10-12 US disclosed
US-4321202-A 1-Methyl-2(alkylimino)pyrrolidines and 1-methyl 2(cycloalkylimino) pyrrolidines GENERAL ELECTRIC COMPANY (US) 1982-03-23 US disclosed
US-4087413-A Crosslinked, linear, acylated polyalkylenepolyamines and process therefor THE DOW CHEMICAL COMPANY (US) 1978-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559586-B2 Compositions containing uretdione groups crosslinking at low temperatures URB2, UQCRB, UQCRC2 ALDH1A1 1357/4885KDM4E 4000/4885L3MBTL1 3338/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.