Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | THRB | P10828 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 4/20 | 0.53 |
| ▸ | CA2 | P00918 | 4/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11260720 | 1.00 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1KDM4EGLAKMT2A | |
| SCHEMBL7641790 | 0.85 | ALDH1A1 (0.86) | ALDH1A1L3MBTL1KDM4EGLAKMT2A | |
| SCHEMBL1132988 | 0.85 | ALDH1A1 (0.86) | ALDH1A1L3MBTL1KDM4EGLAKMT2A | |
| SCHEMBL218110 | 0.83 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1KDM4EGLAKMT2A | |
| SCHEMBL17761949 | 0.83 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1KDM4EGLAKMT2A | |
| SCHEMBL218111 | 0.83 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1KDM4EGLAKMT2A | |
| SCHEMBL3417678 | 0.83 | CA2 (0.69) | ALDH1A1L3MBTL1KDM4EGLAKMT2A | |
| SCHEMBL3417682 | 0.83 | CA2 (0.69) | ALDH1A1L3MBTL1KDM4EGLAKMT2A | |
| SCHEMBL60000 | 0.79 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1KDM4EGLAKMT2A | |
| SCHEMBL59999 | 0.79 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1KDM4EGLAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360466-A | N'-[2,6-Dichloro-4-(substituted-benzylideneamino)phenyl]-N,N-dimethylformamidines | AMERICAN CYANAMID COMPANY (US) | 1982-11-23 | — | — | US | disclosed |