⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Endomorphin-1 SCHEMBL29390342 | 1.00 | — | — | |
| Endomorphin-1 SCHEMBL29577928 | 1.00 | — | — | |
| Endomorphin-1 SCHEMBL29379764 | 1.00 | — | — | |
| SCHEMBL29577213 | 0.95 | DPP3 (0.65) | — | |
| SCHEMBL29772686 | 0.95 | DPP3 (0.65) | — | |
| SCHEMBL13337205 | 0.93 | OPRM1 (0.69) | — | |
| SCHEMBL29576980 | 0.93 | OPRM1 (0.60) | — | |
| SCHEMBL14402545 | 0.92 | KISS1R (0.63) | — | |
| SCHEMBL29648960 | 0.91 | DPP3 (0.69) | — | |
| SCHEMBL30610091 | 0.91 | DPP3 (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024072897-A1 | PEROXIDASE-BASED REPORTERS TO DETECT PROTEASE ACTIVITY AND PROTEIN INTERACTIONS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-04-04 | — | — | WO | disclosed |
| US-20210325365-A1 | BIOLOGICAL NANOPORES HAVING TUNABLE PORE DIAMETERS AND USES THEREOF AS ANALYTICAL TOOLS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2021-10-21 | — | — | US | disclosed |
| EP-3850001-A1 | BIOLOGICAL NANOPORES HAVING TUNABLE PORE DIAMETERS AND USES THEREOF AS ANALYTICAL TOOLS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2021-07-21 | — | — | EP | disclosed |
| WO-2020055246-A1 | BIOLOGICAL NANOPORES HAVING TUNABLE PORE DIAMETERS AND USES THEREOF AS ANALYTICAL TOOLS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-03-19 | — | — | WO | disclosed |