SCHEMBL218143

SCHEMBL218143

CC(C)[C]1C=Cc2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 5/20 0.41
▸ KMT2A Q03164 5/20 0.41
▸ LMNA P02545 4/20 0.41
▸ MAPT P10636 4/20 0.41
▸ ALDH1A1 P00352 2/20 0.41
▸ HSD17B10 Q99714 2/20 0.41
▸ ALOX15 P16050 2/20 0.41
▸ PTPN1 P18031 2/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ BCHE P06276 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ PTPRC P08575 1/20 0.41
▸ THRB P10828 1/20 0.41
▸ PKM P14618 1/20 0.41
▸ IDO1 P14902 1/20 0.41
▸ HPGD P15428 1/20 0.41
▸ ACHE P22303 1/20 0.41
▸ CES1 P23141 1/20 0.41
▸ RECQL P46063 1/20 0.41
▸ PTPN22 Q9Y2R2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28073399 0.94 LMNA (0.38) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL27948941 0.92 LMNA (0.36) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL27933186 0.92 LMNA (0.36) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL27948646 0.92 LMNA (0.36) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL27948681 0.92 LMNA (0.36) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL28806997 0.92 LMNA (0.36) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL27948629 0.92 LMNA (0.36) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL27948676 0.92 LMNA (0.36) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL28810155 0.92 LMNA (0.36) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL27932919 0.92 LMNA (0.36) MEN1KMT2ALMNAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 348 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116589490-A Organic compound, application thereof and organic electroluminescent device comprising same 清华大学 2023-08-15 — — CN claimed
US-9447211-B2 Preparation method of catalyst for polyolefin polymerization and preparation method of polyolefin LG CHEM, LTD. (KR) 2016-09-20 — — US claimed
EP-2837640-B1 METHOD FOR PRODUCING CATALYST FOR POLYOLEFIN POLYMERIZATION AND METHOD FOR PREPARING POLYOLEFIN LG CHEMICAL LTD (KR) 2016-09-07 — — EP claimed
CN-104254547-B The preparation method of catalyst and polyolefinic preparation method for polyolefin polymerization LG化学株式会社 2016-06-08 — — CN claimed
US-20160152742-A1 PREPARATION METHOD OF CATALYST FOR POLYOLEFIN POLYMERIZATION AND PREPARATION METHOD OF POLYOLEFIN LG CHEM, LTD. (KR) 2016-06-02 — — US claimed
EP-1910427-B1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS SK INNOVATION CO LTD (KR) 2015-05-13 — — EP claimed
CN-102977154-B Preparation method of organic-transition metal hydride complexes containing aryl group or alkyl group HANWHA CHEMICAL CORP 2015-05-06 — — CN claimed
EP-2837640-A1 METHOD FOR PRODUCING CATALYST FOR POLYOLEFIN POLYMERIZATION AND METHOD FOR PREPARING POLYOLEFIN LG Chem, Ltd. (KR) 2015-02-18 — — EP claimed
CN-104254547-A METHOD FOR PRODUCING CATALYST FOR POLYOLEFIN POLYMERIZATION AND METHOD FOR PREPARING POLYOLEFIN LG CHEMICAL LTD 2014-12-31 — — CN claimed
US-8822714-B2 More advanced preparation method of organic-transition metal hydride complexes containing aryl group or alkyl group as hydrogen storage materials HANWHA CHEMICAL CORPORATION (KR) 2014-09-02 — — US claimed
US-20090326175-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND a-OLEFINS SK ENERGY CO., LTD. (KR) 2009-12-31 — — US claimed
US-7589042-B2 Arylphenoxy catalyst system for producing ethylene homopolymer or copolymers of ethylene and α-olefins SK CORPORATION (KR) 2009-09-15 — — US claimed
EP-2076551-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND -OLEFINS SK Energy Co., Ltd. (KR) 2009-07-08 — — EP claimed
WO-2008047957-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND α-OLEFINS SK ENERGY CO., LTD. (KR) 2008-04-24 — — WO claimed
US-20070135297-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND a-OLEFINS SK CORPORATION (KR) 2007-06-14 — — US claimed
US-20070004586-A1 Arylphenoxy catalyst system for producing ethylene homopolymer or copolymers of ethylene and alpha-olefins SK CORPORATION (KR) 2007-01-04 — — US claimed
US-6921799-B1 Olefin polymerization process BOREALIS A/S (DK) 2005-07-26 — — US claimed
CN-1157427-C Polymerization method for olefrines �����ɷ� 2004-07-14 — — CN claimed
EP-0993478-B1 OLEFIN POLYMERIZATION PROCESS BOREALIS TECH OY (FI) 2004-04-07 — — EP claimed
CN-1260807-A Polymerization method for olefrines BOREALL AS (DK) 2000-07-19 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090326175-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND a-OLEFINS ESR1, ERO1A, PPOX MEN1 4611/4885KMT2A 3446/4885LMNA 4587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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