SCHEMBL21814476

SCHEMBL21814476

CCC1=C(N)C(=O)c2ccccc2C1=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 1/20 0.53
FGFR2 P21802 1/20 0.53
FGFR4 P22455 1/20 0.53
FGFR3 P22607 1/20 0.53
NPC1 O15118 9/20 0.50
RAB9A P51151 9/20 0.50
ALDH1A1 P00352 7/20 0.50
SMN1; SMN2 Q16637 7/20 0.50
MAPK1 P28482 5/20 0.50
LMNA P02545 5/20 0.50
MAPT P10636 4/20 0.50
POLB P06746 4/20 0.50
NSD2 O96028 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
CYP3A4 P08684 3/20 0.45
TSHR P16473 2/20 0.45
TP53 P04637 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11589728 0.85 NPC1 (0.44) FGFR1FGFR2FGFR4FGFR3NPC1
SCHEMBL30004167 0.84 FGFR1 (0.57) FGFR1FGFR2FGFR4FGFR3NPC1
SCHEMBL5820931 0.84 FGFR1 (0.57) FGFR1FGFR2FGFR4FGFR3NPC1
SCHEMBL21814472 0.78 PTPN1 (0.54) NPC1RAB9AALDH1A1MAPTPOLB
SCHEMBL21814434 0.78 PTPN1 (0.54) NPC1RAB9AALDH1A1MAPTPOLB
SCHEMBL571496 0.77 MAPT (0.56) FGFR1FGFR2FGFR4FGFR3NPC1
SCHEMBL29563346 0.77 RAB9A (0.68) NPC1RAB9AALDH1A1SMN1; SMN2MAPK1
SCHEMBL1510327 0.77 RAB9A (0.68) NPC1RAB9AALDH1A1SMN1; SMN2MAPK1
SCHEMBL29249557 0.76 MAPK1 (0.56) NPC1RAB9AALDH1A1SMN1; SMN2MAPK1
SCHEMBL9627696 0.75 IDO1 (0.60) FGFR1FGFR2FGFR4FGFR3NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3856792-A1 AMINO-QUINONE ANTIPOLYMERANTS AND METHODS OF USING Ecolab USA, Inc. (US) 2021-08-04 EP disclosed
WO-2020068735-A1 AMINO-QUINONE ANTIPOLYMERANTS AND METHODS OF USING ECOLAB USA INC. (US) 2020-04-02 WO disclosed