SCHEMBL30004167

SCHEMBL30004167

CCC1=C(CC)C(=O)c2ccccc2C1=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 1/20 0.57
FGFR2 P21802 1/20 0.57
FGFR4 P22455 1/20 0.57
FGFR3 P22607 1/20 0.57
CDC25B P30305 7/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
LMNA P02545 6/20 0.54
MAPT P10636 6/20 0.54
SMN1; SMN2 Q16637 5/20 0.54
ALDH1A1 P00352 5/20 0.54
RAB9A P51151 3/20 0.54
MAPK1 P28482 3/20 0.54
NPC1 O15118 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
KDM4E B2RXH2 3/20 0.52
POLB P06746 3/20 0.52
BLM P54132 3/20 0.52
S100A4 P26447 3/20 0.52
APAF1 O14727 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5820931 1.00 FGFR1 (0.57) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL14307224 0.89 FGFR1 (0.49) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL571496 0.86 MAPT (0.56) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL21814476 0.84 FGFR1 (0.53) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL28303007 0.84 FGFR1 (0.49) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL8781044 0.84 APAF1 (0.60) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL9627696 0.84 IDO1 (0.60) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL9628254 0.83 MAPT (0.65) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL9627536 0.83 CDC25B (0.53) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL14307223 0.80 CDC25B (0.50) FGFR1FGFR2FGFR4FGFR3CDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110891980-B Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2022-09-30 CN disclosed