SCHEMBL5820931

SCHEMBL5820931

CCC1=C(CC)C(=O)c2ccccc2C1=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 1/20 0.57
FGFR2 P21802 1/20 0.57
FGFR4 P22455 1/20 0.57
FGFR3 P22607 1/20 0.57
CDC25B P30305 7/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
LMNA P02545 6/20 0.54
MAPT P10636 6/20 0.54
SMN1; SMN2 Q16637 5/20 0.54
ALDH1A1 P00352 5/20 0.54
RAB9A P51151 3/20 0.54
MAPK1 P28482 3/20 0.54
NPC1 O15118 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
KDM4E B2RXH2 3/20 0.52
POLB P06746 3/20 0.52
BLM P54132 3/20 0.52
S100A4 P26447 3/20 0.52
APAF1 O14727 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30004167 1.00 FGFR1 (0.57) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL14307224 0.89 FGFR1 (0.49) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL571496 0.86 MAPT (0.56) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL21814476 0.84 FGFR1 (0.53) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL28303007 0.84 FGFR1 (0.49) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL8781044 0.84 APAF1 (0.60) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL9627696 0.84 IDO1 (0.60) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL9628254 0.83 MAPT (0.65) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL9627536 0.83 CDC25B (0.53) FGFR1FGFR2FGFR4FGFR3CDC25B
SCHEMBL14307223 0.80 CDC25B (0.50) FGFR1FGFR2FGFR4FGFR3CDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11613509-B2 Radical polymerization control agent and radical polymerization control method KAWASAKI KASEI CHEMICALS LTD. (JP) 2023-03-28 US disclosed
CN-110891980-B Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2022-09-30 CN disclosed
US-20210122692-A1 RADICAL POLYMERIZATION CONTROL AGENT AND RADICAL POLYMERIZATION CONTROL METHOD KAWASAKI KASEI CHEMICALS LTD. (JP) 2021-04-29 US disclosed
CN-110891980-A Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2020-03-17 CN disclosed
WO-2006107827-A1 SKIN BONDING PROCESS CREIGHTON UNIVERSITY (US) 2006-10-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11613509-B2 Radical polymerization control agent and radical polymerization control method PPOX, NOX4, CROCC FGFR1 4096/4885FGFR2 4418/4885FGFR4 3556/4885
US-20210122692-A1 RADICAL POLYMERIZATION CONTROL AGENT AND RADICAL POLYMERIZATION CONTROL METHOD PPOX, NOX4, CROCC FGFR1 4096/4885FGFR2 4418/4885FGFR4 3556/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.