Phosphine

Phosphine

SCHEMBL21815751

CC(=O)OCCOc1ccccc1.P

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.59
RAB9A P51151 4/20 0.57
NPC1 O15118 3/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
TSHR P16473 1/20 0.57
PKM P14618 2/20 0.56
MTNR1A P48039 1/20 0.56
MTNR1B P49286 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.54
MAPT P10636 1/20 0.54
ALDH1A1 P00352 4/20 0.54
KDM4E B2RXH2 1/20 0.54
MEN1 O00255 1/20 0.54
HPGD P15428 1/20 0.54
NFKB1 P19838 1/20 0.54
NFKB2 Q00653 1/20 0.54
KMT2A Q03164 1/20 0.54
RELA Q04206 1/20 0.54
HSD17B10 Q99714 1/20 0.54
PARP10 Q53GL7 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL144171 0.98 THRB (0.61) THRBRAB9ANPC1SMN1; SMN2TSHR
SCHEMBL21322109 0.93 THRB (0.56) THRBRAB9ANPC1SMN1; SMN2TSHR
SCHEMBL12760859 0.93 THRB (0.56) THRBRAB9ANPC1SMN1; SMN2TSHR
SCHEMBL140660 0.93 THRB (0.56) THRBRAB9ANPC1SMN1; SMN2TSHR
SCHEMBL17921568 0.93 THRB (0.56) THRBRAB9ANPC1SMN1; SMN2TSHR
Acetic Acid Propyl Ester SCHEMBL11290042 0.91 THRB (0.54) THRBRAB9ANPC1SMN1; SMN2TSHR
SCHEMBL8328391 0.89 L3MBTL1 (0.59) THRBRAB9ANPC1SMN1; SMN2TSHR
Acrylic Acid SCHEMBL28795992 0.88 THRB (0.69) THRBRAB9ANPC1SMN1; SMN2TSHR
SCHEMBL10030181 0.88 L3MBTL1 (0.55) THRBRAB9ASMN1; SMN2TSHRPKM
SCHEMBL9151891 0.87 MMP3 (0.55) THRBRAB9ANPC1SMN1; SMN2PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020067800-A1 INK COMPOSITION FOR ORGANIC LIGHT EMITTING DEVICE 주식회사 엘지화학 2020-04-02 WO disclosed