Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19126021 | 0.95 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL20558627 | 0.91 | SMN1; SMN2 (0.41) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL21816777 | 0.86 | KDM4E (0.34) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL20558746 | 0.81 | KDM4E (0.39) | ALDH1A1KDM4EHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL20558544 | 0.79 | SMN1; SMN2 (0.41) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL23698351 | 0.79 | KDM4E (0.39) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL30678550 | 0.79 | KDM4E (0.39) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL31115435 | 0.77 | KDM4E (0.44) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL23698910 | 0.77 | KDM4E (0.38) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL28947251 | 0.77 | KDM4E (0.44) | ALDH1A1KDM4EHPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020067456-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 | 2020-04-02 | — | — | WO | disclosed |