Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TPMT | P51580 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23698897 | 0.86 | KDM4E (0.35) | KDM4EALDH1A1KCNA3HPGDNPSR1 | |
| SCHEMBL23698351 | 0.84 | KDM4E (0.39) | KDM4EALDH1A1KCNA3HPGDNPSR1 | |
| SCHEMBL30678550 | 0.84 | KDM4E (0.39) | KDM4EALDH1A1KCNA3HPGDNPSR1 | |
| SCHEMBL28947251 | 0.83 | KDM4E (0.44) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL31115435 | 0.83 | KDM4E (0.44) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL19126021 | 0.82 | ALDH1A1 (0.39) | KDM4EALDH1A1HPGDNPSR1HSD17B10 | |
| SCHEMBL31417692 | 0.81 | KDM4E (0.37) | KDM4EALDH1A1HPGDNPSR1POLB | |
| SCHEMBL31417774 | 0.80 | KDM4E (0.36) | KDM4EALDH1A1HPGDNPSR1HSD17B10 | |
| SCHEMBL31417569 | 0.80 | KDM4E (0.36) | KDM4EALDH1A1HPGDNPSR1HSD17B10 | |
| SCHEMBL22032138 | 0.80 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12162864-B2 | Condensed-cyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-12-10 | — | — | US | disclosed |
| EP-3858823-A1 | CONDENSED-CYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2021-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12162864-B2 | Condensed-cyclic compound | SLC10A2, VIP, AVPR2 | KDM4E 2962/4885ALDH1A1 1810/4885KCNA3 850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.